Effect of different surgical type of coronary artery bypass grafting on kidney injury

Ming Jen Chan, Cheng Chia Lee, Shao Wei Chen, Feng Chun Tsai, Pyng Jing Lin, Pei Chun Fan, Hsiang Hao Hsu, Ming Yang Chang, Yung Chang Chen, Chih Hsiang Chang*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

7 Scopus citations

Abstract

Acute kidney injury (AKI) after coronary artery bypass grafting (CABG) is associated with a less favorable outcome. Off-pump surgery results in lower kidney dysfunction than conventional on-pump arrest surgery. On-pump arrest surgery results in a lower revascularization rate compared with off-pump surgery. On-pump beating heart (OPBH) CABG combines the advantages of beating heart surgery and cardiopulmonary bypass. This study compared the renal outcomes of 3 cardiac surgical methods. From January 2010 to December 2012, 373 patients who underwent on-pump CABG were enrolled. Propensity analysis was performed to compare the postoperative outcomes of postoperative AKI, renal replacement therapy (RRT), intensive care unit (ICU) stay, mortality, and extubating time. In total, 98 patients received conventional on-pump surgery, 160 received OPBH surgery, and 115 received off-pump surgery. The Society of Thoracic Surgeons scores of these 3 groups were 6.1 ± 13.6, 7.4 ± 13.6, and 5.6 ± 10.9, respectively. Propensity analysis revealed lower AKI incidence in the off-pump group than in the on-pump surgery group. No substantial differences were observed in mortality, RRT, and the ICU stay between the off-pump and OPBH surgery groups. Among the 3 surgical methods, off-pump surgery results in lower AKI incidence. The short-term outcome, including kidney function, of OPBH surgery is similar to that of the off-pump group. Therefore, OPBH surgery is a considerable choice for patients with a high surgical risk.

Original languageEnglish
Article numbere8395
JournalMedicine (United States)
Volume96
Issue number45
DOIs
StatePublished - 01 11 2017

Bibliographical note

Publisher Copyright:
Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc.

Keywords

  • acute kidney injury
  • coronary artery bypass grafting
  • off-pump
  • on-pump

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