Abstract
Statement of Purpose: Cancer stem cells (CSC) are a sub-population of cells and are recently proposed to be the cancer initiating cells responsible for tumor formation, recurrence, metastasis and contribute to cancer resistance. Chemotherapeutic drugs are mostly effective on normal cancer cells leaving CSCs mostly unaffected after treatment. Their quiescence nature makes them prime suspects to be responsible for resistance to anti-proliferative chemotherapy. Our previous study has used hyaluronic acid (HA) based multilayer film system to select liver cancer stem cell colonies. Several studies have demonstrated that low intensity ultrasound can induce stem cell differentiation and also can improve the anti-cancer activity of chemotherapeutic drugs. The goal of this study is to facilitate possibility of differentiation therapy of liver CSCs by using low intensity ultrasound.
Original language | English |
---|---|
Title of host publication | Society for Biomaterials Annual Meeting and Exposition 2019 |
Subtitle of host publication | The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting |
Publisher | Society for Biomaterials |
Pages | 646 |
Number of pages | 1 |
ISBN (Electronic) | 9781510883901 |
State | Published - 2019 |
Event | 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Seattle, United States Duration: 03 04 2019 → 06 04 2019 |
Publication series
Name | Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium |
---|---|
Volume | 40 |
ISSN (Print) | 1526-7547 |
Conference
Conference | 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence |
---|---|
Country/Territory | United States |
City | Seattle |
Period | 03/04/19 → 06/04/19 |
Bibliographical note
Publisher Copyright:© 2019 Omnipress - All rights reserved.