Effect of low intensity ultrasound on the differentiation of liver cancer stem-like cells

I. Chi Lee; Siaka Fadera; Hao Li Liu

Effect of low intensity ultrasound on the differentiation of liver cancer stem-like cells

I. Chi Lee
, Siaka Fadera
, Hao Li Liu

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Statement of Purpose: Cancer stem cells (CSC) are a sub-population of cells and are recently proposed to be the cancer initiating cells responsible for tumor formation, recurrence, metastasis and contribute to cancer resistance. Chemotherapeutic drugs are mostly effective on normal cancer cells leaving CSCs mostly unaffected after treatment. Their quiescence nature makes them prime suspects to be responsible for resistance to anti-proliferative chemotherapy. Our previous study has used hyaluronic acid (HA) based multilayer film system to select liver cancer stem cell colonies. Several studies have demonstrated that low intensity ultrasound can induce stem cell differentiation and also can improve the anti-cancer activity of chemotherapeutic drugs. The goal of this study is to facilitate possibility of differentiation therapy of liver CSCs by using low intensity ultrasound.

Original language	English
Title of host publication	Society for Biomaterials Annual Meeting and Exposition 2019
Subtitle of host publication	The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting
Publisher	Society for Biomaterials
Pages	646
Number of pages	1
ISBN (Electronic)	9781510883901
State	Published - 2019
Event	42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Seattle, United States Duration: 03 04 2019 → 06 04 2019

Publication series

Name	Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
Volume	40
ISSN (Print)	1526-7547

Conference

Conference	42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
Country/Territory	United States
City	Seattle
Period	03/04/19 → 06/04/19

Bibliographical note

Publisher Copyright:
© 2019 Omnipress - All rights reserved.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Cite this

Lee, I. C., Fadera, S., & Liu, H. L. (2019). Effect of low intensity ultrasound on the differentiation of liver cancer stem-like cells. In Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting (pp. 646). (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; Vol. 40). Society for Biomaterials.

Lee, I. Chi ; Fadera, Siaka ; Liu, Hao Li. / Effect of low intensity ultrasound on the differentiation of liver cancer stem-like cells. Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 2019. pp. 646 (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium).

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title = "Effect of low intensity ultrasound on the differentiation of liver cancer stem-like cells",

abstract = "Statement of Purpose: Cancer stem cells (CSC) are a sub-population of cells and are recently proposed to be the cancer initiating cells responsible for tumor formation, recurrence, metastasis and contribute to cancer resistance. Chemotherapeutic drugs are mostly effective on normal cancer cells leaving CSCs mostly unaffected after treatment. Their quiescence nature makes them prime suspects to be responsible for resistance to anti-proliferative chemotherapy. Our previous study has used hyaluronic acid (HA) based multilayer film system to select liver cancer stem cell colonies. Several studies have demonstrated that low intensity ultrasound can induce stem cell differentiation and also can improve the anti-cancer activity of chemotherapeutic drugs. The goal of this study is to facilitate possibility of differentiation therapy of liver CSCs by using low intensity ultrasound.",

author = "Lee, \{I. Chi\} and Siaka Fadera and Liu, \{Hao Li\}",

note = "Publisher Copyright: {\textcopyright} 2019 Omnipress - All rights reserved.; 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence ; Conference date: 03-04-2019 Through 06-04-2019",

year = "2019",

language = "英语",

series = "Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium",

publisher = "Society for Biomaterials",

pages = "646",

booktitle = "Society for Biomaterials Annual Meeting and Exposition 2019",

}

Lee, IC, Fadera, S & Liu, HL 2019, Effect of low intensity ultrasound on the differentiation of liver cancer stem-like cells. in Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium, vol. 40, Society for Biomaterials, pp. 646, 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence, Seattle, United States, 03/04/19.

Effect of low intensity ultrasound on the differentiation of liver cancer stem-like cells. / Lee, I. Chi; Fadera, Siaka; Liu, Hao Li.
Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 2019. p. 646 (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; Vol. 40).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Effect of low intensity ultrasound on the differentiation of liver cancer stem-like cells

AU - Lee, I. Chi

AU - Fadera, Siaka

AU - Liu, Hao Li

PY - 2019

Y1 - 2019

N2 - Statement of Purpose: Cancer stem cells (CSC) are a sub-population of cells and are recently proposed to be the cancer initiating cells responsible for tumor formation, recurrence, metastasis and contribute to cancer resistance. Chemotherapeutic drugs are mostly effective on normal cancer cells leaving CSCs mostly unaffected after treatment. Their quiescence nature makes them prime suspects to be responsible for resistance to anti-proliferative chemotherapy. Our previous study has used hyaluronic acid (HA) based multilayer film system to select liver cancer stem cell colonies. Several studies have demonstrated that low intensity ultrasound can induce stem cell differentiation and also can improve the anti-cancer activity of chemotherapeutic drugs. The goal of this study is to facilitate possibility of differentiation therapy of liver CSCs by using low intensity ultrasound.

AB - Statement of Purpose: Cancer stem cells (CSC) are a sub-population of cells and are recently proposed to be the cancer initiating cells responsible for tumor formation, recurrence, metastasis and contribute to cancer resistance. Chemotherapeutic drugs are mostly effective on normal cancer cells leaving CSCs mostly unaffected after treatment. Their quiescence nature makes them prime suspects to be responsible for resistance to anti-proliferative chemotherapy. Our previous study has used hyaluronic acid (HA) based multilayer film system to select liver cancer stem cell colonies. Several studies have demonstrated that low intensity ultrasound can induce stem cell differentiation and also can improve the anti-cancer activity of chemotherapeutic drugs. The goal of this study is to facilitate possibility of differentiation therapy of liver CSCs by using low intensity ultrasound.

UR - https://www.scopus.com/pages/publications/85065430933

M3 - 会议稿件

AN - SCOPUS:85065430933

T3 - Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium

SP - 646

BT - Society for Biomaterials Annual Meeting and Exposition 2019

PB - Society for Biomaterials

T2 - 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence

Y2 - 3 April 2019 through 6 April 2019

ER -

Lee IC, Fadera S, Liu HL. Effect of low intensity ultrasound on the differentiation of liver cancer stem-like cells. In Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials. 2019. p. 646. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium).

Effect of low intensity ultrasound on the differentiation of liver cancer stem-like cells

Abstract

Publication series

Conference

Bibliographical note

UN SDGs

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Cite this