Effect of postprepared sperm parameters and insemination specimen volume on the outcome of intrauterine insemination.

M. Y. Tsai*, Y. C. Tsai, J. C. Chang, F. T. Kung, J. F. Wu, S. Y. Chang, L. C. Yang

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

Abstract

BACKGROUND: The purpose of the present study was to identify the postprepared sperm parameters affecting the outcome of intrauterine insemination and to find out whether the volume of insemination specimen was a determinant factor in the rate of successful conception. MATERIALS AND METHODS: A retrospective study including 306 couples was designed. The patients were inseminated with either 1.0 or 0.5 ml of prepared specimens. The pregnancy rates were compared using the chi-square test. Logistic regression was chosen for multivariant analysis of the parameters. RESULTS: The only parameter significantly affecting the success rate was the postprepared sperm motility (p = 0.033). The pregnancy rate was 27.91% in cases with > or = 95% sperm motility. Only two patients with less than 75% sperm motility conceived. The pregnancy rates in cases with 0.5 ml and 1.0 ml inseminations were 12.12% and 16.13%, respectively. This difference was statistically insignificant (p = 0.427). CONCLUSION: The postprepared sperm motility was the only parameter predicting the successful rate of intrauterine insemination. Seventy-five percent sperm motility can be used as a cut-off value for selecting patients. The volume of insemination specimen did not influence the outcome. Insemination with 1 ml of fluid was just as effective as insemination with 0.5 ml.

Original languageEnglish
Pages (from-to)265-270
Number of pages6
JournalChang Gung Medical Journal
Volume21
Issue number3
StatePublished - 1998
Externally publishedYes

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