Effect of triacylglycerols on erythrocyte deformability in vitro

C. Y. Hong; L. J. Lai; M. S. Shiao; B. N. Chiang

doi:10.1016/0952-3278(93)90114-C

Effect of triacylglycerols on erythrocyte deformability in vitro

C. Y. Hong^*
, L. J. Lai
, M. S. Shiao
, B. N. Chiang

^*Corresponding author for this work

National Yang Ming Chiao Tung University
Veterans General Hospital-Taipei

Research output: Contribution to journal › Journal Article › peer-review

12 Scopus citations

Abstract

With Reid's filtration technique as a bioassay for evaluating red blood cell (RBC) deformability, we found that tripalmitolein, triolein and trilinolein improved the deformability of calcium-loaded RBC while glycerol, linoleic acid, dilinoleoyl phosphatidyl choline, trilpalmitin, tristearin, trilinolenin and triarachidonin did not. Maximal effect of tripalmitolein, triolein and trilinolein was achieved at 10^-9, 10^-10 and 10^-8 M respectively. We propose that only those triacylglycerols which contain fatty acids with one or two double bonds could modify RBC membrane fluidity and improve RBC deformability.

Original language	English
Pages (from-to)	351-353
Number of pages	3
Journal	Prostaglandins, Leukotrienes and Essential Fatty Acids
Volume	48
Issue number	5
DOIs	https://doi.org/10.1016/0952-3278(93)90114-C
State	Published - 05 1993
Externally published	Yes

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title = "Effect of triacylglycerols on erythrocyte deformability in vitro",

abstract = "With Reid's filtration technique as a bioassay for evaluating red blood cell (RBC) deformability, we found that tripalmitolein, triolein and trilinolein improved the deformability of calcium-loaded RBC while glycerol, linoleic acid, dilinoleoyl phosphatidyl choline, trilpalmitin, tristearin, trilinolenin and triarachidonin did not. Maximal effect of tripalmitolein, triolein and trilinolein was achieved at 10-9, 10-10 and 10-8 M respectively. We propose that only those triacylglycerols which contain fatty acids with one or two double bonds could modify RBC membrane fluidity and improve RBC deformability.",

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T1 - Effect of triacylglycerols on erythrocyte deformability in vitro

AU - Hong, C. Y.

AU - Lai, L. J.

AU - Shiao, M. S.

AU - Chiang, B. N.

PY - 1993/5

Y1 - 1993/5

N2 - With Reid's filtration technique as a bioassay for evaluating red blood cell (RBC) deformability, we found that tripalmitolein, triolein and trilinolein improved the deformability of calcium-loaded RBC while glycerol, linoleic acid, dilinoleoyl phosphatidyl choline, trilpalmitin, tristearin, trilinolenin and triarachidonin did not. Maximal effect of tripalmitolein, triolein and trilinolein was achieved at 10-9, 10-10 and 10-8 M respectively. We propose that only those triacylglycerols which contain fatty acids with one or two double bonds could modify RBC membrane fluidity and improve RBC deformability.

AB - With Reid's filtration technique as a bioassay for evaluating red blood cell (RBC) deformability, we found that tripalmitolein, triolein and trilinolein improved the deformability of calcium-loaded RBC while glycerol, linoleic acid, dilinoleoyl phosphatidyl choline, trilpalmitin, tristearin, trilinolenin and triarachidonin did not. Maximal effect of tripalmitolein, triolein and trilinolein was achieved at 10-9, 10-10 and 10-8 M respectively. We propose that only those triacylglycerols which contain fatty acids with one or two double bonds could modify RBC membrane fluidity and improve RBC deformability.

UR - https://www.scopus.com/pages/publications/0027299667

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DO - 10.1016/0952-3278(93)90114-C

M3 - 文章

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AN - SCOPUS:0027299667

SN - 0952-3278

VL - 48

SP - 351

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JO - Prostaglandins, Leukotrienes and Essential Fatty Acids

JF - Prostaglandins, Leukotrienes and Essential Fatty Acids

IS - 5

ER -

Effect of triacylglycerols on erythrocyte deformability in vitro

Abstract

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