TY - JOUR
T1 - Effect of triacylglycerols on erythrocyte deformability in vitro
AU - Hong, C. Y.
AU - Lai, L. J.
AU - Shiao, M. S.
AU - Chiang, B. N.
PY - 1993/5
Y1 - 1993/5
N2 - With Reid's filtration technique as a bioassay for evaluating red blood cell (RBC) deformability, we found that tripalmitolein, triolein and trilinolein improved the deformability of calcium-loaded RBC while glycerol, linoleic acid, dilinoleoyl phosphatidyl choline, trilpalmitin, tristearin, trilinolenin and triarachidonin did not. Maximal effect of tripalmitolein, triolein and trilinolein was achieved at 10-9, 10-10 and 10-8 M respectively. We propose that only those triacylglycerols which contain fatty acids with one or two double bonds could modify RBC membrane fluidity and improve RBC deformability.
AB - With Reid's filtration technique as a bioassay for evaluating red blood cell (RBC) deformability, we found that tripalmitolein, triolein and trilinolein improved the deformability of calcium-loaded RBC while glycerol, linoleic acid, dilinoleoyl phosphatidyl choline, trilpalmitin, tristearin, trilinolenin and triarachidonin did not. Maximal effect of tripalmitolein, triolein and trilinolein was achieved at 10-9, 10-10 and 10-8 M respectively. We propose that only those triacylglycerols which contain fatty acids with one or two double bonds could modify RBC membrane fluidity and improve RBC deformability.
UR - https://www.scopus.com/pages/publications/0027299667
U2 - 10.1016/0952-3278(93)90114-C
DO - 10.1016/0952-3278(93)90114-C
M3 - 文章
C2 - 8321871
AN - SCOPUS:0027299667
SN - 0952-3278
VL - 48
SP - 351
EP - 353
JO - Prostaglandins, Leukotrienes and Essential Fatty Acids
JF - Prostaglandins, Leukotrienes and Essential Fatty Acids
IS - 5
ER -