TY - GEN
T1 - Effect on lesion detectability of proximity to anatomical boundaries in emission tomography
AU - Kulkarni, S.
AU - Khurd, P.
AU - Hsiao, I.
AU - Gindi, G.
PY - 2005
Y1 - 2005
N2 - In emission tomography (ET) comprising PET and SPECT, anatomical information derived from intra-patient coregistered CT or MR scans can be incorporated into the ET reconstruction. The increasing availability of PET-CT and SPECT-CT has engendered renewed interest in anatomical priors. Our interest is in exploring the efficacy of such side information for lesion detectability. In simulation studies we used an idealized model of anatomical side information incorporated into a SPECT MAP (maximum a posteriori) reconstruction, and a channelized Hotelling observer (CHO) whose performance emulates that of humans in such detection tasks. We observed that detectability appears to vary little with or without anatomical side information unless the lesion is tightly constrained by anatomical boundaries. Our preliminary studies thus imply a limited utility for anatomical side information for this task.
AB - In emission tomography (ET) comprising PET and SPECT, anatomical information derived from intra-patient coregistered CT or MR scans can be incorporated into the ET reconstruction. The increasing availability of PET-CT and SPECT-CT has engendered renewed interest in anatomical priors. Our interest is in exploring the efficacy of such side information for lesion detectability. In simulation studies we used an idealized model of anatomical side information incorporated into a SPECT MAP (maximum a posteriori) reconstruction, and a channelized Hotelling observer (CHO) whose performance emulates that of humans in such detection tasks. We observed that detectability appears to vary little with or without anatomical side information unless the lesion is tightly constrained by anatomical boundaries. Our preliminary studies thus imply a limited utility for anatomical side information for this task.
UR - http://www.scopus.com/inward/record.url?scp=33846615996&partnerID=8YFLogxK
U2 - 10.1109/NSSMIC.2005.1596760
DO - 10.1109/NSSMIC.2005.1596760
M3 - 会议稿件
AN - SCOPUS:33846615996
SN - 0780392213
SN - 9780780392212
T3 - IEEE Nuclear Science Symposium Conference Record
SP - 2150
EP - 2154
BT - 2005 IEEE Nuclear Science Symposium Conference Record -Nuclear Science Symposium and Medical Imaging Conference
T2 - Nuclear Science Symposium Conference Record, 2005 IEEE
Y2 - 23 October 2005 through 29 October 2005
ER -