Effects of thyroidectomy and thyroxine replacement on the responsiveness of the anterior pituitaries from male rats to thyrotropin-releasing hormone in vitro

T. K. Tang; S. W. Wang; P. S. Wang

doi:10.1007/BF01940719

Effects of thyroidectomy and thyroxine replacement on the responsiveness of the anterior pituitaries from male rats to thyrotropin-releasing hormone in vitro

T. K. Tang^*
, S. W. Wang
, P. S. Wang

^*Corresponding author for this work

National Yang Ming Chiao Tung University

Research output: Contribution to journal › Journal Article › peer-review

15 Scopus citations

Abstract

Thyroidectomy decreased prolactin concentrations in the anterior pituitary (AP) and serum of the male rat. The amount of basal and thyrotropin-releasing hormone (TRH)-stimulated release of prolactin by AP in vitro was lower in thyroidectomized (Tx) rats than in sham Tx rats. These results suggest that the inhibitory effects of thyroidectomy on pituitary and serum prolactin in male rats are mediated in part by the reduction of the production and spontaneous release of prolactin and the responsiveness of prolactin to TRH.

Original language	English
Pages (from-to)	1031-1034
Number of pages	4
Journal	Experientia
Volume	42
Issue number	9
DOIs	https://doi.org/10.1007/BF01940719
State	Published - 09 1986
Externally published	Yes

Keywords

TRH
Thyroidectomy
rat TSH
rat prolactin

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10.1007/BF01940719

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title = "Effects of thyroidectomy and thyroxine replacement on the responsiveness of the anterior pituitaries from male rats to thyrotropin-releasing hormone in vitro",

abstract = "Thyroidectomy decreased prolactin concentrations in the anterior pituitary (AP) and serum of the male rat. The amount of basal and thyrotropin-releasing hormone (TRH)-stimulated release of prolactin by AP in vitro was lower in thyroidectomized (Tx) rats than in sham Tx rats. These results suggest that the inhibitory effects of thyroidectomy on pituitary and serum prolactin in male rats are mediated in part by the reduction of the production and spontaneous release of prolactin and the responsiveness of prolactin to TRH.",

keywords = "TRH, Thyroidectomy, rat TSH, rat prolactin",

author = "Tang, \{T. K.\} and Wang, \{S. W.\} and Wang, \{P. S.\}",

year = "1986",

month = sep,

doi = "10.1007/BF01940719",

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volume = "42",

pages = "1031--1034",

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T1 - Effects of thyroidectomy and thyroxine replacement on the responsiveness of the anterior pituitaries from male rats to thyrotropin-releasing hormone in vitro

AU - Tang, T. K.

AU - Wang, S. W.

AU - Wang, P. S.

PY - 1986/9

Y1 - 1986/9

N2 - Thyroidectomy decreased prolactin concentrations in the anterior pituitary (AP) and serum of the male rat. The amount of basal and thyrotropin-releasing hormone (TRH)-stimulated release of prolactin by AP in vitro was lower in thyroidectomized (Tx) rats than in sham Tx rats. These results suggest that the inhibitory effects of thyroidectomy on pituitary and serum prolactin in male rats are mediated in part by the reduction of the production and spontaneous release of prolactin and the responsiveness of prolactin to TRH.

AB - Thyroidectomy decreased prolactin concentrations in the anterior pituitary (AP) and serum of the male rat. The amount of basal and thyrotropin-releasing hormone (TRH)-stimulated release of prolactin by AP in vitro was lower in thyroidectomized (Tx) rats than in sham Tx rats. These results suggest that the inhibitory effects of thyroidectomy on pituitary and serum prolactin in male rats are mediated in part by the reduction of the production and spontaneous release of prolactin and the responsiveness of prolactin to TRH.

KW - TRH

KW - Thyroidectomy

KW - rat TSH

KW - rat prolactin

UR - https://www.scopus.com/pages/publications/0022529493

U2 - 10.1007/BF01940719

DO - 10.1007/BF01940719

M3 - 文章

C2 - 3093263

AN - SCOPUS:0022529493

SN - 0014-4754

VL - 42

SP - 1031

EP - 1034

JO - Experientia

JF - Experientia

IS - 9

ER -

Effects of thyroidectomy and thyroxine replacement on the responsiveness of the anterior pituitaries from male rats to thyrotropin-releasing hormone in vitro

Abstract

Keywords

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