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Electrospun nanofibrous scaffolds for soft tissue regeneration

  • Dave Wei Chih Chen
  • , Shih Jung Liu*
  • *Corresponding author for this work
  • Chang Gung Memorial Hospital

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Abstract

This chapter aims to provide a general overview on the applications of electrospun biodegradable nanofibrous scaffolds for soft tissue regeneration. The soft tissue and extracellular matrix is first introduced. The tissue or cellar host responses to injury, including inflammation, wound healing and foreign-body reaction, is outlined. The fabrication of nanofibrous scaffold made of biodegradable polymers via electrospinning is then presented. The properties of the fabricated scaffolds, including morphology, mechanical strength and biodegradability, are discussed in detail. The development of electrospun scaffolds for soft tissue regeneration in various clinical applications is also reviewed. Finally, the future trend for electrospun nanofibrous scaffolds is addressed.

Original languageEnglish
Title of host publicationSpringer Series in Biomaterials Science and Engineering
PublisherSpringer Science and Business Media, LLC
Pages271-301
Number of pages31
DOIs
StatePublished - 2016

Publication series

NameSpringer Series in Biomaterials Science and Engineering
Volume8
ISSN (Print)2195-0644
ISSN (Electronic)2195-0652

Bibliographical note

Publisher Copyright:
© Springer-Verlag GmbH Germany 2017.

Keywords

  • Electrospun nanofibrous scaffolds
  • Foreignbody reaction
  • Inflammation
  • Soft tissue regeneration
  • Tissue engineering
  • Wound healing

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