Elevated Risk of Mood Disorders after the Occurrence of Recurrent Retinal Detachment: A Population-Based Cohort Study

Chia Yi Lee; Hung Chi Chen; Jing Yang Huang; Chi Chun Lai; Shun Fa Yang; Wei Chi Wu

doi:10.1159/000521290

Elevated Risk of Mood Disorders after the Occurrence of Recurrent Retinal Detachment: A Population-Based Cohort Study

Chia Yi Lee, Hung Chi Chen, Jing Yang Huang, Chi Chun Lai, Shun Fa Yang^*, Wei Chi Wu^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

2 Scopus citations

Abstract

Introduction: The aim of this study was to investigate the risk of mood disorders in patients who experienced retinal detachment (RD) by using the National Health Insurance Research Database in Taiwan. Methods: Participants with a diagnosis of RD were regarded as the study group, and an age- and sex-matched group without a diagnosis of RD served as the control group. The outcomes related to mood disorders after RD included: (1) psychiatric outpatient department visits; (2) behavioural therapy; (3) sleep or anxiety-related disorders; and (4) major depressive disorder (MDD). Results: A total of 4,129 participants diagnosed with RD and 16,516 non-RD individuals were enrolled in the study. There were no significant differences in the four mood disorder-related outcomes between the study and control groups. However, the patients with recurrent RD who received more than two treatments and female patients with RD who needed surgical treatment showed a higher probability of developing MDD than did the non-RD subjects (incidence rate: 0.96 vs. 0.36; adjusted hazard ratio [aHR]: 2.382, 95% confidence interval [CI]: 1.032-5.496, log-rank p = 0.0325; and aHR: 6.895, 95% CI: 1.659-28.656, log-rank p = 0.0060, respectively). Conclusion: Patients with recurrent RD and multiple surgeries and females with RD who needed surgical treatment were at greater risk for developing MDD.

Original language	English
Pages (from-to)	249-257
Number of pages	9
Journal	Ophthalmologica
Volume	245
Issue number	3
DOIs	https://doi.org/10.1159/000521290
State	Published - 01 06 2022
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2022

Keywords

Epidemiology
Gender
Major depression disorder
Mood disorder
Retinal detachment

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10.1159/000521290

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title = "Elevated Risk of Mood Disorders after the Occurrence of Recurrent Retinal Detachment: A Population-Based Cohort Study",

abstract = "Introduction: The aim of this study was to investigate the risk of mood disorders in patients who experienced retinal detachment (RD) by using the National Health Insurance Research Database in Taiwan. Methods: Participants with a diagnosis of RD were regarded as the study group, and an age- and sex-matched group without a diagnosis of RD served as the control group. The outcomes related to mood disorders after RD included: (1) psychiatric outpatient department visits; (2) behavioural therapy; (3) sleep or anxiety-related disorders; and (4) major depressive disorder (MDD). Results: A total of 4,129 participants diagnosed with RD and 16,516 non-RD individuals were enrolled in the study. There were no significant differences in the four mood disorder-related outcomes between the study and control groups. However, the patients with recurrent RD who received more than two treatments and female patients with RD who needed surgical treatment showed a higher probability of developing MDD than did the non-RD subjects (incidence rate: 0.96 vs. 0.36; adjusted hazard ratio [aHR]: 2.382, 95\% confidence interval [CI]: 1.032-5.496, log-rank p = 0.0325; and aHR: 6.895, 95\% CI: 1.659-28.656, log-rank p = 0.0060, respectively). Conclusion: Patients with recurrent RD and multiple surgeries and females with RD who needed surgical treatment were at greater risk for developing MDD.",

keywords = "Epidemiology, Gender, Major depression disorder, Mood disorder, Retinal detachment",

author = "Lee, \{Chia Yi\} and Chen, \{Hung Chi\} and Huang, \{Jing Yang\} and Lai, \{Chi Chun\} and Yang, \{Shun Fa\} and Wu, \{Wei Chi\}",

note = "Publisher Copyright: {\textcopyright} 2022 ",

year = "2022",

month = jun,

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doi = "10.1159/000521290",

language = "英语",

volume = "245",

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T1 - Elevated Risk of Mood Disorders after the Occurrence of Recurrent Retinal Detachment

T2 - A Population-Based Cohort Study

AU - Lee, Chia Yi

AU - Chen, Hung Chi

AU - Huang, Jing Yang

AU - Lai, Chi Chun

AU - Yang, Shun Fa

AU - Wu, Wei Chi

PY - 2022/6/1

Y1 - 2022/6/1

N2 - Introduction: The aim of this study was to investigate the risk of mood disorders in patients who experienced retinal detachment (RD) by using the National Health Insurance Research Database in Taiwan. Methods: Participants with a diagnosis of RD were regarded as the study group, and an age- and sex-matched group without a diagnosis of RD served as the control group. The outcomes related to mood disorders after RD included: (1) psychiatric outpatient department visits; (2) behavioural therapy; (3) sleep or anxiety-related disorders; and (4) major depressive disorder (MDD). Results: A total of 4,129 participants diagnosed with RD and 16,516 non-RD individuals were enrolled in the study. There were no significant differences in the four mood disorder-related outcomes between the study and control groups. However, the patients with recurrent RD who received more than two treatments and female patients with RD who needed surgical treatment showed a higher probability of developing MDD than did the non-RD subjects (incidence rate: 0.96 vs. 0.36; adjusted hazard ratio [aHR]: 2.382, 95% confidence interval [CI]: 1.032-5.496, log-rank p = 0.0325; and aHR: 6.895, 95% CI: 1.659-28.656, log-rank p = 0.0060, respectively). Conclusion: Patients with recurrent RD and multiple surgeries and females with RD who needed surgical treatment were at greater risk for developing MDD.

AB - Introduction: The aim of this study was to investigate the risk of mood disorders in patients who experienced retinal detachment (RD) by using the National Health Insurance Research Database in Taiwan. Methods: Participants with a diagnosis of RD were regarded as the study group, and an age- and sex-matched group without a diagnosis of RD served as the control group. The outcomes related to mood disorders after RD included: (1) psychiatric outpatient department visits; (2) behavioural therapy; (3) sleep or anxiety-related disorders; and (4) major depressive disorder (MDD). Results: A total of 4,129 participants diagnosed with RD and 16,516 non-RD individuals were enrolled in the study. There were no significant differences in the four mood disorder-related outcomes between the study and control groups. However, the patients with recurrent RD who received more than two treatments and female patients with RD who needed surgical treatment showed a higher probability of developing MDD than did the non-RD subjects (incidence rate: 0.96 vs. 0.36; adjusted hazard ratio [aHR]: 2.382, 95% confidence interval [CI]: 1.032-5.496, log-rank p = 0.0325; and aHR: 6.895, 95% CI: 1.659-28.656, log-rank p = 0.0060, respectively). Conclusion: Patients with recurrent RD and multiple surgeries and females with RD who needed surgical treatment were at greater risk for developing MDD.

KW - Epidemiology

KW - Gender

KW - Major depression disorder

KW - Mood disorder

KW - Retinal detachment

UR - https://www.scopus.com/pages/publications/85132455369

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JF - Ophthalmologica

IS - 3

ER -

Elevated Risk of Mood Disorders after the Occurrence of Recurrent Retinal Detachment: A Population-Based Cohort Study

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