EMG spike trains of succinylcholine-induced fasciculations in myalgic patients

Paul W.F. Poon, P. W. Lui*, L. H. Chow, F. K. Lam, Francis H.Y. Chan, Y. M. Lin

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

4 Scopus citations


Single spike activity from the surface electromyogram (EMG) of fasciculations induced by succinylcholine (Sch) were studied from limb muscles (biceps, triceps, anterior tibialis and gastrocnemius) in 100 female patients. About 2/3 of them (n = 72) also received nondepolarizing neuromuscular pretreatment (atracurium or vecuronium). We observed from 20% of EMG records in the myalgic (but not in the nonmyalgic) patients, sustained spike trains (mean duration 1.47 s) that resembled motor units firing at physiologically high rates (mean 21.7 spikes/s). The finding reflects Sch's distal actions at the muscle spindle. The implications for myalgia and the possible involvement of micro damage at the extrafusal muscles are discussed.

Original languageEnglish
Pages (from-to)206-210
Number of pages5
JournalElectroencephalography and Clinical Neurophysiology - Electromyography and Motor Control
Issue number3
StatePublished - 06 1996
Externally publishedYes


  • Electromyogram
  • Fasciculations
  • Myalgia
  • Succinylcholine


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