TY - JOUR
T1 - Endogenous klebsiella endophthalmitis associated with klebsiella pneumoniae pneumonia
AU - Chen, Kuan Jen
AU - Hwang, Yih Shiou
AU - Chen, Yen Po
AU - Lai, Chi Chun
AU - Chen, Tun Lu
AU - Wang, Nan Kai
PY - 2009/6
Y1 - 2009/6
N2 - Purpose: To investigate the management, bacterial strains, antibiotic sensitivities, and visual outcomes in patients with Klebsiella pneumoniae pneumonia and endogenous Klebsiella endophthalmitis. Methods: Data were collected for treatments, antibiotic sensitivity patterns, and final visual outcomes. Results: The study included 10 eyes of 9 patients with a median age of 42 years (range, 0-86 years). Diabetes mellitus was the most common comorbid risk factor (n = 5, 56%). Nine eyes (90%) were treated with intravitreal antibiotics, and one with pars plana vitrectomy and intravitreal antibiotics. One eye achieved a favorable visual acuity of 20/20; however, 6 eyes developed vision of no light perception, including 2 of evisceration. Two nosocomial K. pneumoniae isolates were extended-spectrum--lactamase-producing strains, which demonstrated the resistance to amikacin and ceftazidime. Conclusions: Ophthalmologists and physicians should be aware of Klebsiella pneumonia as a possible cause of endogenous endophthalmitis, and endogenous Klebsiella endophthalmitis usually causes poor visual outcomes.
AB - Purpose: To investigate the management, bacterial strains, antibiotic sensitivities, and visual outcomes in patients with Klebsiella pneumoniae pneumonia and endogenous Klebsiella endophthalmitis. Methods: Data were collected for treatments, antibiotic sensitivity patterns, and final visual outcomes. Results: The study included 10 eyes of 9 patients with a median age of 42 years (range, 0-86 years). Diabetes mellitus was the most common comorbid risk factor (n = 5, 56%). Nine eyes (90%) were treated with intravitreal antibiotics, and one with pars plana vitrectomy and intravitreal antibiotics. One eye achieved a favorable visual acuity of 20/20; however, 6 eyes developed vision of no light perception, including 2 of evisceration. Two nosocomial K. pneumoniae isolates were extended-spectrum--lactamase-producing strains, which demonstrated the resistance to amikacin and ceftazidime. Conclusions: Ophthalmologists and physicians should be aware of Klebsiella pneumonia as a possible cause of endogenous endophthalmitis, and endogenous Klebsiella endophthalmitis usually causes poor visual outcomes.
KW - Endogenous endophthalmitis
KW - Extended-spectrum- lactamase
KW - Intravitreal antibiotics
KW - Klebsiella pneumoniae
KW - Pneumonia
UR - http://www.scopus.com/inward/record.url?scp=68849092558&partnerID=8YFLogxK
U2 - 10.1080/09273940902752250
DO - 10.1080/09273940902752250
M3 - 文章
C2 - 19585357
AN - SCOPUS:68849092558
SN - 0927-3948
VL - 17
SP - 153
EP - 159
JO - Ocular Immunology and Inflammation
JF - Ocular Immunology and Inflammation
IS - 3
ER -