Endogenous klebsiella endophthalmitis associated with klebsiella pneumoniae pneumonia

Kuan Jen Chen*, Yih Shiou Hwang, Yen Po Chen, Chi Chun Lai, Tun Lu Chen, Nan Kai Wang

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

17 Scopus citations

Abstract

Purpose: To investigate the management, bacterial strains, antibiotic sensitivities, and visual outcomes in patients with Klebsiella pneumoniae pneumonia and endogenous Klebsiella endophthalmitis. Methods: Data were collected for treatments, antibiotic sensitivity patterns, and final visual outcomes. Results: The study included 10 eyes of 9 patients with a median age of 42 years (range, 0-86 years). Diabetes mellitus was the most common comorbid risk factor (n = 5, 56%). Nine eyes (90%) were treated with intravitreal antibiotics, and one with pars plana vitrectomy and intravitreal antibiotics. One eye achieved a favorable visual acuity of 20/20; however, 6 eyes developed vision of no light perception, including 2 of evisceration. Two nosocomial K. pneumoniae isolates were extended-spectrum--lactamase-producing strains, which demonstrated the resistance to amikacin and ceftazidime. Conclusions: Ophthalmologists and physicians should be aware of Klebsiella pneumonia as a possible cause of endogenous endophthalmitis, and endogenous Klebsiella endophthalmitis usually causes poor visual outcomes.

Original languageEnglish
Pages (from-to)153-159
Number of pages7
JournalOcular Immunology and Inflammation
Volume17
Issue number3
DOIs
StatePublished - 06 2009

Keywords

  • Endogenous endophthalmitis
  • Extended-spectrum- lactamase
  • Intravitreal antibiotics
  • Klebsiella pneumoniae
  • Pneumonia

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