Epstein-barr virus and its oncogenesis

Hsin Pai Li, Mei Chao, Shu Jen Chen, Yu Sun Chang

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

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Abstract

Epstein-Barr virus (EBV), a γ-herpesvirus, has been studied for over 40 years, since its first discovery which dates back to 1964. Although more than 90% of the human population have been infected with EBV at early childhood, the majority remain asymptomatic. EBV has been proven to be the etiological agent associated with various human cancers, such as Burkitt's lymphoma (BL), Hodgkin's disease (HD), T-cell lymphoma, nasopharyngeal carcinoma (NPC), and a subset of gastric carcinoma. In this chapter, we specifically discuss the oncogenic properties of EBV latent genes, small RNAs, and microRNAs (miRNAs) that are expressed in EBV-associated cancers.

Original languageEnglish
Title of host publicationHuman Oncogenic Viruses
PublisherWorld Scientific Publishing Co.
Pages209-267
Number of pages59
ISBN (Electronic)9789812833471
ISBN (Print)9812833463, 9789812833464
DOIs
StatePublished - 01 01 2009

Bibliographical note

Publisher Copyright:
© 2010 by World Scientific Publishing Co. Pte. Ltd. All rights reserved.

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