TY - JOUR
T1 - Eupatozansins A-C, sesquiterpene lactones from Eupatorium chinense var. tozanense
AU - Liaw, Chia Ching
AU - Kuo, Yao Haur
AU - Hwang, Tsong Long
AU - Shen, Ya Ching
PY - 2008/11
Y1 - 2008/11
N2 - Phytochemical investigation of Eupatorium chinense var. tozanense has resulted in the isolation of three new germacranolides, designated as eupatozansins A-C (1-3), along with five known compounds, (5S,6R,7R,8R)-8- angeloyloxy-2-oxoguaia-1(10),3,11(13)-trien-12,6-olide (4), costunolide (5), leptocarpin (6), 2α-hydroxyeupatolide 8-O-angelate (7), and quercetin (8). The structures of the new compounds were identified by 1D and 2D NMR experiments, as well as high-resolution mass spectrometry. The in vitro cytotoxic activities of compounds 1-8 were evaluated.
AB - Phytochemical investigation of Eupatorium chinense var. tozanense has resulted in the isolation of three new germacranolides, designated as eupatozansins A-C (1-3), along with five known compounds, (5S,6R,7R,8R)-8- angeloyloxy-2-oxoguaia-1(10),3,11(13)-trien-12,6-olide (4), costunolide (5), leptocarpin (6), 2α-hydroxyeupatolide 8-O-angelate (7), and quercetin (8). The structures of the new compounds were identified by 1D and 2D NMR experiments, as well as high-resolution mass spectrometry. The in vitro cytotoxic activities of compounds 1-8 were evaluated.
UR - http://www.scopus.com/inward/record.url?scp=57149105765&partnerID=8YFLogxK
U2 - 10.1002/hlca.200890227
DO - 10.1002/hlca.200890227
M3 - 文章
AN - SCOPUS:57149105765
SN - 0018-019X
VL - 91
SP - 2115
EP - 2121
JO - Helvetica Chimica Acta
JF - Helvetica Chimica Acta
IS - 11
ER -