Evaluation of post-operative inflammation following penetrating keratoplasty - A laser flare-cell meter study

R. J.F. Tsai*, H. K. Ma, J. J.Y. Chen

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review


In order to understand whether preoperative corneal status of recipient and the addition of other intraocular procedures will affect the post-operative inflammatory reaction following penetrating keratoplasty, 35 eyes of 35 patients (M:F = 26:9, mean age = 51.1 ± 19.9 years old) were grouped according to anticipated outcome into good, fair, and poor prognosis group. Each group was subdivided into those with keratoplasty only and those with additional procedures (cataract extraction, removal or implantation of IOL, or release of broad synechia of iris). He-Ne laser flare-cell photometry was done within 1 week, 1 month and 3 months post-operatively. The follow-up period ranged from 3 to 9 months (average = 5.6 ± 2.1 months). All data were compared by multivariate analysis. We found that there is no significant difference in aqueous protein concentration in any time interval among patients of different prognostic group; however, there is significant difference in all time interval between those who received additional procedures and those who didn't. Therefore, we proposed that the short-term post-operative inflammation following penetrating keratoplasty is related less to preoperative corneal status but more to the addition of other surgeries; more tissue damage in the latter condition may be the cause of a more severe inflammatory response.

Original languageEnglish
Pages (from-to)45-52
Number of pages8
JournalTzu Chi Medical Journal
Issue number1
StatePublished - 1997
Externally publishedYes


  • aqueous protein concentration
  • inflammation
  • laser flare-cell meter
  • penetrating keratoplasty


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