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Event-related evoked potentials in Alzheimer's disease by a tool-using gesture paradigm

  • Chang Gung University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

4 Scopus citations

Abstract

The Alzheimer's disease (AD) has a wide spectrum of symptoms, ranging from cognition dysfunction to behavior disturbances and functional impairment. The evoked cerebral potentials by specific paradigms are useful for disclosing neuropsychological activities. The evolution of AD is accompanied by progressive cognitive impairment which may result in a difficulty to recognize or comprehend gestures. In the present study, a visual tool-using gesture paradigm was employed to assess the cognitive functions of 16 probable AD patients, 17 subjects mild cognitive impairment (MCI), and 17 age-matched control subjects. Each subject was conducted by visual stimuli by a series of pictures, each displaying randomly a gesture with correctly or incorrectly using a tool. The P300 amplitude was further used as a parameter to build classifiers based on support vector machine.

Original languageEnglish
Title of host publication2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Pages4299-4301
Number of pages3
DOIs
StatePublished - 2013
Event2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 - Osaka, Japan
Duration: 03 07 201307 07 2013

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)1557-170X

Conference

Conference2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Country/TerritoryJapan
CityOsaka
Period03/07/1307/07/13

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