Ex-vivo study of cavitation-enhanced heating by combining low (40 kHz) and high (566 kHz) frequency ultrasound

Hao Li Liu*, Tzu Ching Shih, Wen Shiang Chen, Bing Yuh Lu

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review

1 Scopus citations

Abstract

The objective of this study is to demonstrate the cavitation-enhanced heating via combining low-frequency ultrasound during an ultrasound thermal treatment. Two ultrasound transducers were used: A 566-kHz spherical transducer was used to generate the thermal lesion while another 40-kHz planar transducer was positioned orthogonally with its axis across the focus of the high-frequency one. The emission and backscattered signals from the bubble activity were also recorded during the heating process by a needle hydrophone. Compared to the lesion formed by exposure to the focused transducer only, its size increased up to 200% and 140% in the axial direction and cross section, respectively. The enlarged lesion, rather than being in tadpole shape, symmetrically in the focal direction, which implied that the cavitation-enhanced lesions could be generated without losing its penetration ability. This study demonstrates an easy and effective approach to enlarge the final size of a thermal lesion by applying low frequency ultrasound simultaneously, and would be important if a large-volume and deep-sited thermal lesion by ultrasound ablation was necessary.

Original languageEnglish
Pages (from-to)1477-1480
Number of pages4
JournalProceedings - IEEE Ultrasonics Symposium
Volume2
StatePublished - 2004
Externally publishedYes
Event2004 IEEE Ultrasonics Symposium - Montreal, Que., Canada
Duration: 23 08 200427 08 2004

Fingerprint

Dive into the research topics of 'Ex-vivo study of cavitation-enhanced heating by combining low (40 kHz) and high (566 kHz) frequency ultrasound'. Together they form a unique fingerprint.

Cite this