Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography

Yin Shen Cheng; Tai Ang Wang; Hsiang Chieh Lee; Meng Tsan Tsai

doi:10.1117/12.2674964

Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography

Yin Shen Cheng, Tai Ang Wang, Hsiang Chieh Lee, Meng Tsan Tsai^*

^*Corresponding author for this work

Department of Electrical Engineering

National Taiwan University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

In this study, a swept-source optical coherence tomography (SS-OCT) system and a Raman fiber laser with high laser output are used to investigate the photothermal effect on biological tissue. An optical focuser is connected to the Raman fiber laser to focus the laser power on the specific area of the tissue. To simultaneously observe the induced photothermal effect, a dynamic algorithm is used in the process to produce dynamic image of the tissue from time-series OCT images. The results show that with dynamic images, we can identify the extent and area of laser ablation with time. Moreover, after merging the dynamic image and the original OCT image, we can indicate the ablated area in the tissue apart from the surrounding area without ablation.

Original language	English
Title of host publication	Optical Coherence Imaging Techniques and Imaging in Scattering Media V
Editors	Benjamin J. Vakoc, Maciej Wojtkowski, Yoshiaki Yasuno
Publisher	SPIE
ISBN (Electronic)	9781510664739
DOIs	https://doi.org/10.1117/12.2674964
State	Published - 2023
Event	Optical Coherence Imaging Techniques and Imaging in Scattering Media V 2023 - Munich, Germany Duration: 25 06 2023 → 29 06 2023

Publication series

Name	Proceedings of SPIE - The International Society for Optical Engineering
Volume	12632
ISSN (Print)	0277-786X
ISSN (Electronic)	1996-756X

Conference

Conference	Optical Coherence Imaging Techniques and Imaging in Scattering Media V 2023
Country/Territory	Germany
City	Munich
Period	25/06/23 → 29/06/23

Bibliographical note

Publisher Copyright:
© 2023 SPIE. All rights reserved.

Keywords

laser therapy
optical coherence tomography
photothermolysis

Access to Document

10.1117/12.2674964

Cite this

Cheng, Y. S., Wang, T. A., Lee, H. C., & Tsai, M. T. (2023). Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography. In B. J. Vakoc, M. Wojtkowski, & Y. Yasuno (Eds.), Optical Coherence Imaging Techniques and Imaging in Scattering Media V Article 1263221 (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 12632). SPIE. https://doi.org/10.1117/12.2674964

Cheng, Yin Shen ; Wang, Tai Ang ; Lee, Hsiang Chieh et al. / Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography. Optical Coherence Imaging Techniques and Imaging in Scattering Media V. editor / Benjamin J. Vakoc ; Maciej Wojtkowski ; Yoshiaki Yasuno. SPIE, 2023. (Proceedings of SPIE - The International Society for Optical Engineering).

@inproceedings{159b3de5703e4944b86c1a0dd2832b2f,

title = "Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography",

abstract = "In this study, a swept-source optical coherence tomography (SS-OCT) system and a Raman fiber laser with high laser output are used to investigate the photothermal effect on biological tissue. An optical focuser is connected to the Raman fiber laser to focus the laser power on the specific area of the tissue. To simultaneously observe the induced photothermal effect, a dynamic algorithm is used in the process to produce dynamic image of the tissue from time-series OCT images. The results show that with dynamic images, we can identify the extent and area of laser ablation with time. Moreover, after merging the dynamic image and the original OCT image, we can indicate the ablated area in the tissue apart from the surrounding area without ablation.",

keywords = "laser therapy, optical coherence tomography, photothermolysis",

author = "Cheng, {Yin Shen} and Wang, {Tai Ang} and Lee, {Hsiang Chieh} and Tsai, {Meng Tsan}",

note = "Publisher Copyright: {\textcopyright} 2023 SPIE. All rights reserved.; Optical Coherence Imaging Techniques and Imaging in Scattering Media V 2023 ; Conference date: 25-06-2023 Through 29-06-2023",

year = "2023",

doi = "10.1117/12.2674964",

language = "英语",

series = "Proceedings of SPIE - The International Society for Optical Engineering",

publisher = "SPIE",

editor = "Vakoc, {Benjamin J.} and Maciej Wojtkowski and Yoshiaki Yasuno",

booktitle = "Optical Coherence Imaging Techniques and Imaging in Scattering Media V",

address = "美国",

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Cheng, YS, Wang, TA, Lee, HC & Tsai, MT 2023, Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography. in BJ Vakoc, M Wojtkowski & Y Yasuno (eds), Optical Coherence Imaging Techniques and Imaging in Scattering Media V., 1263221, Proceedings of SPIE - The International Society for Optical Engineering, vol. 12632, SPIE, Optical Coherence Imaging Techniques and Imaging in Scattering Media V 2023, Munich, Germany, 25/06/23. https://doi.org/10.1117/12.2674964

Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography. / Cheng, Yin Shen; Wang, Tai Ang; Lee, Hsiang Chieh et al.
Optical Coherence Imaging Techniques and Imaging in Scattering Media V. ed. / Benjamin J. Vakoc; Maciej Wojtkowski; Yoshiaki Yasuno. SPIE, 2023. 1263221 (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 12632).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography

AU - Cheng, Yin Shen

AU - Wang, Tai Ang

AU - Lee, Hsiang Chieh

AU - Tsai, Meng Tsan

PY - 2023

Y1 - 2023

N2 - In this study, a swept-source optical coherence tomography (SS-OCT) system and a Raman fiber laser with high laser output are used to investigate the photothermal effect on biological tissue. An optical focuser is connected to the Raman fiber laser to focus the laser power on the specific area of the tissue. To simultaneously observe the induced photothermal effect, a dynamic algorithm is used in the process to produce dynamic image of the tissue from time-series OCT images. The results show that with dynamic images, we can identify the extent and area of laser ablation with time. Moreover, after merging the dynamic image and the original OCT image, we can indicate the ablated area in the tissue apart from the surrounding area without ablation.

AB - In this study, a swept-source optical coherence tomography (SS-OCT) system and a Raman fiber laser with high laser output are used to investigate the photothermal effect on biological tissue. An optical focuser is connected to the Raman fiber laser to focus the laser power on the specific area of the tissue. To simultaneously observe the induced photothermal effect, a dynamic algorithm is used in the process to produce dynamic image of the tissue from time-series OCT images. The results show that with dynamic images, we can identify the extent and area of laser ablation with time. Moreover, after merging the dynamic image and the original OCT image, we can indicate the ablated area in the tissue apart from the surrounding area without ablation.

KW - laser therapy

KW - optical coherence tomography

KW - photothermolysis

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T3 - Proceedings of SPIE - The International Society for Optical Engineering

BT - Optical Coherence Imaging Techniques and Imaging in Scattering Media V

A2 - Vakoc, Benjamin J.

A2 - Wojtkowski, Maciej

A2 - Yasuno, Yoshiaki

PB - SPIE

T2 - Optical Coherence Imaging Techniques and Imaging in Scattering Media V 2023

Y2 - 25 June 2023 through 29 June 2023

ER -

Cheng YS, Wang TA, Lee HC, Tsai MT. Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography. In Vakoc BJ, Wojtkowski M, Yasuno Y, editors, Optical Coherence Imaging Techniques and Imaging in Scattering Media V. SPIE. 2023. 1263221. (Proceedings of SPIE - The International Society for Optical Engineering). doi: 10.1117/12.2674964

Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography

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