Abstract
The expression of 20 known cellular proto-oncogenes in human well-differentiated hepatoma cell line Hep3B and poorly-differentiated hepatoma cell line HA22T/VGH was studied by Northern blot hybridization. Among the cellular proto-oncogenes examined, both cell lines express protein kinase genes including fps, mos and raf; PDGF B chain sis gene; GTP/GDP binding protein gene Ha-ras and nuclear protein genes including fos and myc. The expression of yes, abl, ros, src, erb-B, erb-A, fms, Ki-ras, myb, rel and bas genes was not detected in both cell lines.
Original language | English |
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Pages (from-to) | 141-150 |
Number of pages | 10 |
Journal | Chinese Journal of Microbiology and Immunology |
Volume | 21 |
Issue number | 3 |
State | Published - 08 1988 |
Externally published | Yes |