Expression of oncogenes in human hepatoma cell lines.

L. P. Ting*, K. S. Jeng, C. K. Chou, T. S. Su, C. P. Hu, F. H. Wong, H. K. Chang, C. M. Chang

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

3 Scopus citations


The expression of 20 known cellular proto-oncogenes in human well-differentiated hepatoma cell line Hep3B and poorly-differentiated hepatoma cell line HA22T/VGH was studied by Northern blot hybridization. Among the cellular proto-oncogenes examined, both cell lines express protein kinase genes including fps, mos and raf; PDGF B chain sis gene; GTP/GDP binding protein gene Ha-ras and nuclear protein genes including fos and myc. The expression of yes, abl, ros, src, erb-B, erb-A, fms, Ki-ras, myb, rel and bas genes was not detected in both cell lines.

Original languageEnglish
Pages (from-to)141-150
Number of pages10
JournalChinese Journal of Microbiology and Immunology
Issue number3
StatePublished - 08 1988
Externally publishedYes


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