TY - JOUR
T1 - Extrapulmonary tuberculosis in chronic hemodialysis patients
AU - Chuang, Feng Rong
AU - Lee, Chih Hsiung
AU - Wang, I. Kuan
AU - Chen, Jin Bor
AU - Wu, Mai Szu
PY - 2003
Y1 - 2003
N2 - Background. The incidence of extrapulmonary tuberculosis is higher in dialysis than general population. The aim of the study was to characterize clinical picture in dialysis patients, who developed extrapulmonary tuberculosis. Methods. We retrospectively investigated the hemodialysis patients with extrapulmonary tuberculosis. 2208 hemodialysis patients were reviewed for extrapulmonary tuberculosis from October 1986 to January 2001. Results. Seventeen patients (10 male, 7 female) were enrolled. The mean age was 57.4 ± 12.4 years. The sites for extrapulmonary tuberculosis were peritoneum (35.3%, 6/17), cervical lymph node (17.6%, 3/17), bone marrow (5.9%, 1/17), spine (5.9%, 1/17), knee (5.9%, 1/17), brain (5.9%, 1/17), pericardium (5.9%, 1/17), cutaneous tissue (5.9%, 1/17) and genitourinary system (5.9%, 1/17). Fourteen of 15 tissue-biopsy specimens from suspicious sites revealed granulomatous inflammation. There were low yield in mycobacteria culture (11.1%, 1/9) and PCR (33.3%, 2/6). Three patients died during the treatment of the disease. Conclusion. Extrapulmonary tuberculosis constitutes a major part of tuberculosis in dialysis patients. Tissue biopsy with invasive procedures, such as laparoscopy or laparotomy, may be necessary if clinical presentations are suspicious.
AB - Background. The incidence of extrapulmonary tuberculosis is higher in dialysis than general population. The aim of the study was to characterize clinical picture in dialysis patients, who developed extrapulmonary tuberculosis. Methods. We retrospectively investigated the hemodialysis patients with extrapulmonary tuberculosis. 2208 hemodialysis patients were reviewed for extrapulmonary tuberculosis from October 1986 to January 2001. Results. Seventeen patients (10 male, 7 female) were enrolled. The mean age was 57.4 ± 12.4 years. The sites for extrapulmonary tuberculosis were peritoneum (35.3%, 6/17), cervical lymph node (17.6%, 3/17), bone marrow (5.9%, 1/17), spine (5.9%, 1/17), knee (5.9%, 1/17), brain (5.9%, 1/17), pericardium (5.9%, 1/17), cutaneous tissue (5.9%, 1/17) and genitourinary system (5.9%, 1/17). Fourteen of 15 tissue-biopsy specimens from suspicious sites revealed granulomatous inflammation. There were low yield in mycobacteria culture (11.1%, 1/9) and PCR (33.3%, 2/6). Three patients died during the treatment of the disease. Conclusion. Extrapulmonary tuberculosis constitutes a major part of tuberculosis in dialysis patients. Tissue biopsy with invasive procedures, such as laparoscopy or laparotomy, may be necessary if clinical presentations are suspicious.
KW - Extrapulmonary tuberculosis
KW - Hemodialysis
KW - Laparoscopy
KW - Laparotomy
UR - http://www.scopus.com/inward/record.url?scp=0141841757&partnerID=8YFLogxK
U2 - 10.1081/JDI-120024289
DO - 10.1081/JDI-120024289
M3 - 文章
C2 - 14575282
AN - SCOPUS:0141841757
SN - 0886-022X
VL - 25
SP - 739
EP - 746
JO - Renal Failure
JF - Renal Failure
IS - 5
ER -