Fabrication of highly tubular porous chitosan/poly (DL lactic-cO-glycolic acid) (PLGA) nanocomposite structures intended for tissue engineering scaffold applications

Zhixiang Cui*, Hai Bin Zhao, Yi Yan Peng, Xiao Feng Wang, Jian Han, Lih Sheng Turng, Changyu Shen

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In this study, highly tubular porous chitosan/poly (DL lactic-co-glycolic acid) (PLGA) nanocomposite structures were produced via electrospinning and unidirectional freeze drying techniques. The 3D porous structure of chitosan/PLGA was characterized by scanning electron microscopy (SEM). The properties of the chitosan/PLGA nanocomposite, including porosity, water absorption, and mechanical properties, were investigated. The results showed that a highly tubular porous structure with nanotopography was formed and the compressive modulus increased greatly due to the addition of PLGA nanofibers.

Original languageEnglish
Title of host publication70th Annual Technical Conference of the Society of Plastics Engineers 2012, ANTEC 2012
Pages159-163
Number of pages5
StatePublished - 2012
Externally publishedYes
Event70th Annual Technical Conference of the Society of Plastics Engineers 2012, ANTEC 2012 - Orlando, FL, United States
Duration: 02 04 201204 04 2012

Publication series

NameAnnual Technical Conference - ANTEC, Conference Proceedings
Volume1

Conference

Conference70th Annual Technical Conference of the Society of Plastics Engineers 2012, ANTEC 2012
Country/TerritoryUnited States
CityOrlando, FL
Period02/04/1204/04/12

Keywords

  • Electrospinning
  • Freeze-drying
  • Highly tubular
  • Porous nanocomposites
  • Tissue engineering scaffolds

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