Fabrication of magnetic hydrogels stencils using microfluidic system for cell patterning techniques

  • Hwan You Chang*
  • , Chien Yu Fu
  • , Chun Yen Lin
  • , Wen Chen Chu
  • , Tsung Pao Wang
  • , Cheng Hsien Liu
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In this study, we describe a method applied magnetic force and photoresponsive hydrogels for cell patterning. A magnetic microparticle- containing hydrogel stencil is first generated using the photolithography technique. This stencil can be remotely controlled with a magnet and used to define the area for cell adhesion in the cell culture dish or microfluidic system. Subsequently, generating heterotypic cell patterning and stacking cell sheets layer-by-layer for tissue reconstruction can be achieved with repeating the patterning process. We believe our magnetic hydrogel-based cell patterning method is a useful tool to generate cell sheet for drug screening and fundamental biology study.

Original languageEnglish
Title of host publicationTechnical Proceedings of the 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011
Pages532-534
Number of pages3
StatePublished - 2011
Externally publishedYes
EventNanotechnology 2011: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational - 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011 - Boston, MA, United States
Duration: 13 06 201116 06 2011

Publication series

NameTechnical Proceedings of the 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011
Volume2

Conference

ConferenceNanotechnology 2011: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational - 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011
Country/TerritoryUnited States
CityBoston, MA
Period13/06/1116/06/11

Keywords

  • Cell patterning
  • Magnetic particles
  • Microfluidic systems and drug screening
  • Photoresponsive hydrogel

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