Factors related to medication non-adherence for patients with hypertension in Taiwan

Aims and objective. To characterise a Taiwanese population and to examine the prevalence of antihypertensive medication non-adherence and how the cultural/clinical factors were associated with non-adherence in Taiwan. Background. Antihypertensive medication non-adherence is a significant clinical issue in the United States. However, little is known about hypertension (HTN) control and cultural/clinical factors related to non-adherence in Taiwan. Design. A convenience sample survey design was used. Method. Data were gathered from a convenience sample of 200 subjects recruited from a large teaching hospital. Medication non-adherence and cultural/clinical factors were recorded using various self-administered questionnaires, and blood pressure was taken twice for each participant. Results. The mean age of the participants was 60·4 (SD 11·5years) including 62% men. Two-thirds had less than a high school education (64·5%), and the majority of them were married (86·0%) and lived with family or close friends (93·5%). The average length of HTN diagnosis was 8·6years (SD 9·0years). Medication non-adherence rate was 47·5%, and uncontrolled HTN rate was 49·0%. Some participants (17·0%) used Chinese herbs for treating their disease (e.g. cough) and promoting health in addition to their regular antihypertensive medications. Two factors were found to be statistically significant for predicting medication non-adherence: Lower Perceived Susceptibility to Specific Diseases [OR=1·15 (95%CI, 1·01-1·31)] and Longer Length of HTN Diagnosis [OR=1·06 (95%CI, 1·01-1·12)]. Conclusions. Taiwanese at risk of non-adherence included those who perceived lower susceptibility to specific diseases and had been diagnosed with HTN for a longer time. Those using herbs need to be studied for an impact of herbs on their adherence behaviour. Relevance to clinical practice. These findings can help guide the development of culturally sensitive and clinically appropriate nursing interventions for HTN management in Taiwan.