Feature selection and combination criteria for improving predictive accuracy in protein structure classification

Chun Yuan Lin*, Ken Li Lin, Chuen Der Huang, Hsiu Ming Chang, Chiao Yun Yang, Chin Teng Lin, Chuan Yi Tang, D. Frank Hsu

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

10 Scopus citations

Abstract

The classification of protein structures is essential for their function determination in bioinformatics. The success of the protein structure classification depends on two factors: the computational methods used and the features selected. In this paper, we use a combinatorial fusion analysis technique to facilitate feature selection and combination for improving predictive accuracy in protein structure classification. When applying these criteria to our previous work, the resulting classification has an overall prediction accuracy rate of 87% for four classes and 69.6% for 27 folding categories. These rates are significantly higher than our previous work and demonstrate that combinatorial fusion is a valuable method for protein structure classification.

Original languageEnglish
Title of host publicationProceedings - BIBE 2005
Subtitle of host publication5th IEEE Symposium on Bioinformatics and Bioengineering
Pages311-315
Number of pages5
DOIs
StatePublished - 2005
Externally publishedYes
EventBIBE 2005: 5th IEEE Symposium on Bioinformatics and Bioengineering - Minneapolis, MN, United States
Duration: 19 10 200521 10 2005

Publication series

NameProceedings - BIBE 2005: 5th IEEE Symposium on Bioinformatics and Bioengineering
Volume2005

Conference

ConferenceBIBE 2005: 5th IEEE Symposium on Bioinformatics and Bioengineering
Country/TerritoryUnited States
CityMinneapolis, MN
Period19/10/0521/10/05

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