Abstract
OBJECTIVE: To provide better preconceptional and prenatal counselling to patients with sjögren syndrome (SS).
METHODS: In total, 2 100 143 pregnancies between 2004 and 2014 were identified in the Taiwan National Health Insurance database and birth registry. The maternal history of SS was ascertained, and data were compared between pregnant women with and without SS. We assessed the odds ratios and 95% CIs of fetal-neonatal and maternal outcomes.
RESULTS: There were 449 pregnancies in women with SS and 2 099 694 pregnancies in women without SS. The risks of still birth [odds ratio (OR) = 2.14, 95% CI = 1.01, 4.55], low birth weight (<2500 g, OR = 2.53, 95% CI = 1.92, 3.33), small for gestational age (OR = 2.03, 95% CI = 1.57, 2.03) and fetal distress (OR = 1.72, 95% CI = 1.2, 2.45) as well as maternal risks of pulmonary oedema (OR = 11.64, 95% CI = 1.62, 83.48), shock (OR = 6.07, 95% CI = 1.51, 24.3) and respiratory distress (OR = 5.61, 95% CI = 1.39, 22.6) were higher in the SS group than in the non-SS group.
CONCLUSION: Women with SS have significant risks of adverse fetal-neonatal and maternal outcomes and must undergo prenatal counselling to understand the risks involved before conception.
| Original language | English |
|---|---|
| Pages (from-to) | 2820-2828 |
| Number of pages | 9 |
| Journal | Rheumatology (United Kingdom) |
| Volume | 62 |
| Issue number | 8 |
| DOIs | |
| State | Published - 01 08 2023 |
Bibliographical note
© The Author(s) 2023. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: [email protected].Keywords
- SS
- Taiwan
- fetal outcomes
- maternal outcomes
- pregnancy
- Humans
- Stillbirth
- Fetal Growth Retardation
- Pregnancy
- Pregnancy Outcome/epidemiology
- Sjogren's Syndrome/epidemiology
- Female
- Family
- Infant, Newborn
- Prenatal Care