First trimester diagnosis of holoprosencephaly and cyclopia with triploidy by transvaginal three-dimensional ultrasonography

Te Yao Hsu; Shiuh Young Chang; Chia Yu Ou; Zen Hung Chen; Wen Lin Tsai; Ming Shan Chang; Yung Kuei Soong

doi:10.1016/S0301-2115(00)00453-X

First trimester diagnosis of holoprosencephaly and cyclopia with triploidy by transvaginal three-dimensional ultrasonography

Te Yao Hsu^*
, Shiuh Young Chang
, Chia Yu Ou
, Zen Hung Chen
, Wen Lin Tsai
, Ming Shan Chang
, Yung Kuei Soong

^*Corresponding author for this work

Chang Gung Memorial Hospital

Research output: Contribution to journal › Journal Article › peer-review

26 Scopus citations

Abstract

We present the prenatal three-dimensional (3D) ultrasound findings in a case of holoprosencephaly and cyclopia at 11 weeks gestation. Only holoprosencephaly with missing cyclopia were initially diagnosed because suboptimal views of the fetal face were obtained with transvaginal two-dimensional (2D) ultrasonography due to fetal position. Chromosomes identified by analysis of a fluid sample from early amniocentesis demonstrated a triploidy (69, XXX), spontaneous fetal demise occurred at 12 weeks and the pregnancy was terminated. This case demonstrated the usefulness of transvaginal 3D ultrasonography in establishing the final diagnosis.

Original language	English
Pages (from-to)	235-237
Number of pages	3
Journal	European Journal of Obstetrics and Gynecology and Reproductive Biology
Volume	96
Issue number	2
DOIs	https://doi.org/10.1016/S0301-2115(00)00453-X
State	Published - 2001
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cyclopia
Holoprosencephaly
Three-dimensional ultrasonography
Triploidy

Access to Document

10.1016/S0301-2115(00)00453-X

Cite this

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title = "First trimester diagnosis of holoprosencephaly and cyclopia with triploidy by transvaginal three-dimensional ultrasonography",

abstract = "We present the prenatal three-dimensional (3D) ultrasound findings in a case of holoprosencephaly and cyclopia at 11 weeks gestation. Only holoprosencephaly with missing cyclopia were initially diagnosed because suboptimal views of the fetal face were obtained with transvaginal two-dimensional (2D) ultrasonography due to fetal position. Chromosomes identified by analysis of a fluid sample from early amniocentesis demonstrated a triploidy (69, XXX), spontaneous fetal demise occurred at 12 weeks and the pregnancy was terminated. This case demonstrated the usefulness of transvaginal 3D ultrasonography in establishing the final diagnosis.",

keywords = "Cyclopia, Holoprosencephaly, Three-dimensional ultrasonography, Triploidy",

author = "Hsu, \{Te Yao\} and Chang, \{Shiuh Young\} and Ou, \{Chia Yu\} and Chen, \{Zen Hung\} and Tsai, \{Wen Lin\} and Chang, \{Ming Shan\} and Soong, \{Yung Kuei\}",

year = "2001",

doi = "10.1016/S0301-2115(00)00453-X",

language = "英语",

volume = "96",

pages = "235--237",

journal = "European Journal of Obstetrics and Gynecology and Reproductive Biology",

issn = "0301-2115",

publisher = "Elsevier Ireland Ltd",

number = "2",

}

TY - JOUR

T1 - First trimester diagnosis of holoprosencephaly and cyclopia with triploidy by transvaginal three-dimensional ultrasonography

AU - Hsu, Te Yao

AU - Chang, Shiuh Young

AU - Ou, Chia Yu

AU - Chen, Zen Hung

AU - Tsai, Wen Lin

AU - Chang, Ming Shan

AU - Soong, Yung Kuei

PY - 2001

Y1 - 2001

N2 - We present the prenatal three-dimensional (3D) ultrasound findings in a case of holoprosencephaly and cyclopia at 11 weeks gestation. Only holoprosencephaly with missing cyclopia were initially diagnosed because suboptimal views of the fetal face were obtained with transvaginal two-dimensional (2D) ultrasonography due to fetal position. Chromosomes identified by analysis of a fluid sample from early amniocentesis demonstrated a triploidy (69, XXX), spontaneous fetal demise occurred at 12 weeks and the pregnancy was terminated. This case demonstrated the usefulness of transvaginal 3D ultrasonography in establishing the final diagnosis.

AB - We present the prenatal three-dimensional (3D) ultrasound findings in a case of holoprosencephaly and cyclopia at 11 weeks gestation. Only holoprosencephaly with missing cyclopia were initially diagnosed because suboptimal views of the fetal face were obtained with transvaginal two-dimensional (2D) ultrasonography due to fetal position. Chromosomes identified by analysis of a fluid sample from early amniocentesis demonstrated a triploidy (69, XXX), spontaneous fetal demise occurred at 12 weeks and the pregnancy was terminated. This case demonstrated the usefulness of transvaginal 3D ultrasonography in establishing the final diagnosis.

KW - Cyclopia

KW - Holoprosencephaly

KW - Three-dimensional ultrasonography

KW - Triploidy

UR - https://www.scopus.com/pages/publications/0034989380

U2 - 10.1016/S0301-2115(00)00453-X

DO - 10.1016/S0301-2115(00)00453-X

M3 - 文章

C2 - 11384818

AN - SCOPUS:0034989380

SN - 0301-2115

VL - 96

SP - 235

EP - 237

JO - European Journal of Obstetrics and Gynecology and Reproductive Biology

JF - European Journal of Obstetrics and Gynecology and Reproductive Biology

IS - 2

ER -

First trimester diagnosis of holoprosencephaly and cyclopia with triploidy by transvaginal three-dimensional ultrasonography

Abstract

UN SDGs

Keywords

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