@inproceedings{3535263123834b9b8baeaddf5cdd8357,
title = "Fluorescence in situ hybridization (FISH) microfluidic platform for detection of her-2 over-expression in cancer cells",
abstract = "Detection of cancer biomarkers has become increasingly important for the early diagnosis, prognosis, and treatment of cancer. Genetic biomarkers like HER2 have been associated with many types of cancers including breast cancer and gastric cancer. Furthermore, Ilerceptin therapeutics has been found to be particularly effective for patients with an overexpression of HER2 to improve overall survival rates. Fluorescence in situ hybridization (FISH) has been commonly used for HER2 over-expression. However, it requires expensive reagents and skilled personnel. In this work, a novel, integrated FISH microfluidic platform capable of performing the entire FISH protocol automatically to diagnose HER-2 over-expression was reported. Experimental results showed that the developed platform could achieve comparable results when compared with the manual process.",
keywords = "Cancer biomarker, FISH, HER2, Ilerceptin",
author = "Kao, {Kai Jie} and Tai, {Chien Hsuan} and Luo, {Wen Yi} and Yeh, {Ta Sen} and Lee, {Gwo Bin}",
year = "2013",
language = "英语",
isbn = "9781632666246",
series = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013",
publisher = "Chemical and Biological Microsystems Society",
pages = "509--511",
booktitle = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013",
note = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 ; Conference date: 27-10-2013 Through 31-10-2013",
}