Four new compounds from edible algae Cladosiphon okamuranus and Chlorella sorokiniana and their bioactivities

In the present work, two new compounds, known as mozukulins A (1) and B (2), together with three known compounds, including eicosapentaenoic acid (EPA), henicosahexaene and phytol, were characterized from edible brown alga Cladosiphon okamuranus. The anti-inflammatory activity results demonstrated that eicosapentaenoic acid (EPA) displayed significant bioactivity. We did not observe significant bioactivity for the two new compounds (1 and 2), which indicates the need for further studies in the future. In addition, the constituent analysis of Chlorella sorokiniana from Taiwan produced chlorellatins A (3) and B (4) that are reported from the natural sources for the first time, as well as eight other known compounds. Moreover, the lutein content was as high as 4.54% in the fraction of extracts.