Free flap reconstruction for early stage tongue squamous cell carcinoma: surgical margin and recurrence

Chien Chi Lu, Yung An Tsou*, Chun Hung Hua, Ming Hsui Tsai

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

8 Scopus citations


Background: To identify the difference of surgical margin and recurrence status of early stage tongue carcinoma via wide excision in a single institution with and without free flap reconstruction. Objective: Survey whether the reconstruction methods for early tongue cancer affects disease control, survival outcomes. Methods: This was a retrospective study and patients with early tongue cancer underwent surgery via tumor ablation with (group 1 = 56) or without free flap reconstruction (group 2 = 291). Results: The percentage of patients with free margin less than 5 mm was higher in the group 2 than in group 1 (49.48% vs. 19.64%, p <.001), as the mean free margin was significantly larger in group 1 than in group 2 (7.88 mm vs. 5.68 mm; p <.001). Despite higher number of T2 stage patients in group 1 (89.29%), the group 1 resulted in a significant lower recurrence rate (p =.024). Conclusions: The utilization of free flap reconstruction for early stage tongue cancer achieved a large pathologic free margin and had relative lower recurrence and good survival rates.

Original languageEnglish
Pages (from-to)945-950
Number of pages6
JournalActa Oto-Laryngologica
Issue number10
StatePublished - 03 10 2018
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2018, © 2018 Acta Oto-Laryngologica AB (Ltd).


  • Free flap reconstruction
  • primary closure
  • recurrence
  • squamous cell carcinoma
  • tongue


Dive into the research topics of 'Free flap reconstruction for early stage tongue squamous cell carcinoma: surgical margin and recurrence'. Together they form a unique fingerprint.

Cite this