From phase diagram to the design of strontium-containing carrier

Ying Cen Chen, Pei Yi Hsu, W. Tuan*, Po Liang Lai

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

7 Scopus citations


Strontium (Sr) ions are known for its role on increasing bone mineral density. However, a high dosage through mouth may cause many side effects. An alternative to provide a low but steady release at the location of bone defect is therefore explored. In the present study, various amounts of strontium sulfate (SrSO4) were dissolved into calcium sulfate (CaSO4) at elevated temperatures. The release of Sr ions from the (Ca,Sr)SO4 solid solution into various aqueous solutions was then measured. Through the control of Sr content in (Ca,Sr)SO4, the Sr amount releasing into the aqueous solutions could be tailored. After implanting a solid solution into distal femur in rat, a low release of Sr into blood was confirmed.

Original languageEnglish
Pages (from-to)677-684
Number of pages8
JournalJournal of Asian Ceramic Societies
Issue number3
StatePublished - 02 07 2020

Bibliographical note

Publisher Copyright:
© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of The Korean Ceramic Society and The Ceramic Society of Japan.


  • Phase diagram
  • biomedical applications
  • calcium sulfate
  • solid solution
  • strontium


Dive into the research topics of 'From phase diagram to the design of strontium-containing carrier'. Together they form a unique fingerprint.

Cite this