TY - JOUR
T1 - Gastric leiomyosarcoma
T2 - A clinicopathological review
AU - Sheen-Chen, Shyr-Ming
AU - Chou, F. F.
AU - Eng, Hock-Liew
AU - Chen, J. J.
AU - Lee, C. M.
AU - Wan, Y. L.
PY - 1994
Y1 - 1994
N2 - Objective: To report our experience of eight patients with primary gastric leiomyosarcoma. Design: Retrospective study. Setting: Teaching hospital, Taiwan. Subjects: 8 patients who presented with primary gastric leiomyosarcoma between 1986 and 1990. Main outcome measures: Endoscopic, radiological, and histopathological features, DNA ploidy, and outcome. Results: Abdominal pain and gastrointestinal bleeding were the most common presenting symptoms. In 5 of the 7 patients who had endoscopy preoperatively a diagnosis of submucosal tumour was made, but a definite diagnosis of leiomyosarcoma was made in only 3. A provisional diagnosis of leiomyosarcoma was made in 3 of the 4 patients who had computed tomography. All patients underwent some form of gastric resection ranging from palliative resection to total gastrectomy. Patients in whom the tumour had invaded adjacent organs had a poor prognosis. Histopathological grading of tumours correlated well with DNA ploidy. Conclusion: Both histopathological grading and DNA ploidy could be helpful objective prognostic criteria in patients with primary gastric leiomyosarcoma.
AB - Objective: To report our experience of eight patients with primary gastric leiomyosarcoma. Design: Retrospective study. Setting: Teaching hospital, Taiwan. Subjects: 8 patients who presented with primary gastric leiomyosarcoma between 1986 and 1990. Main outcome measures: Endoscopic, radiological, and histopathological features, DNA ploidy, and outcome. Results: Abdominal pain and gastrointestinal bleeding were the most common presenting symptoms. In 5 of the 7 patients who had endoscopy preoperatively a diagnosis of submucosal tumour was made, but a definite diagnosis of leiomyosarcoma was made in only 3. A provisional diagnosis of leiomyosarcoma was made in 3 of the 4 patients who had computed tomography. All patients underwent some form of gastric resection ranging from palliative resection to total gastrectomy. Patients in whom the tumour had invaded adjacent organs had a poor prognosis. Histopathological grading of tumours correlated well with DNA ploidy. Conclusion: Both histopathological grading and DNA ploidy could be helpful objective prognostic criteria in patients with primary gastric leiomyosarcoma.
KW - DNA ploidy
KW - Gastric leiomyosarcoma
UR - http://www.scopus.com/inward/record.url?scp=0028020852&partnerID=8YFLogxK
M3 - 文章
C2 - 7888469
AN - SCOPUS:0028020852
SN - 1102-4151
VL - 160
SP - 681
EP - 687
JO - European Journal of Surgery, Acta Chirurgica
JF - European Journal of Surgery, Acta Chirurgica
IS - 12
ER -