Gene extraction and identification tumor/cancer for microarray data of ovarian cancer

  • Zne Jung Lee*
  • , Shih Wei Lin
  • , Cheng Chic Veritas Hsu
  • , Yen Po Huang
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

A typical microarray data of ovarian cancer consists of the expressions of tens of thousands of genes on a genomic scale. To avoid higher computational complexity, we want to find the most likely differentially expressed gene that best explain the effects of tumor/cancer for ovarian cancer. In this paper, we derive a hybrid approach for extracting and evaluating informative genes from microarray data of ovarian cancer. Furthermore, the expression patterns of extracted genes are used to identify tumor/cancer for ovarian cancer. In the proposed approach, the method analysis of variance (ANOVA) will, using P-value, test gene expressions that are significantly different in microarray data. The genetic algorithm is applied to extract genes and then the support vector machine is processed to identify tumor/cancer for ovarian cancer. We show that this extracted set of genes can be used to significantly identify ovarian tumors (OVT) and ovarian cancers (OVCA).

Original languageEnglish
Title of host publication2006 IEEE Region 10 Conference, TENCON 2006
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Print)1424405491, 9781424405497
DOIs
StatePublished - 2006
Externally publishedYes
Event2006 IEEE Region 10 Conference, TENCON 2006 - Hong Kong, China
Duration: 14 11 200617 11 2006

Publication series

NameIEEE Region 10 Annual International Conference, Proceedings/TENCON
ISSN (Print)2159-3442
ISSN (Electronic)2159-3450

Conference

Conference2006 IEEE Region 10 Conference, TENCON 2006
Country/TerritoryChina
CityHong Kong
Period14/11/0617/11/06

Fingerprint

Dive into the research topics of 'Gene extraction and identification tumor/cancer for microarray data of ovarian cancer'. Together they form a unique fingerprint.

Cite this