Genital human papillomavirus infections in Taiwan

Y. P. Tsao, K. Y. Yang, C. P. Han, C. S. Yin, Y. F. Yang, S. L. Chen*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

8 Scopus citations

Abstract

OBJECTIVES: Identification and typing of HPV infections in genital condyloma and normal cytological cervix. METHODS: Cervical cells from 289 Pap cases with normal cytological findings were examined for HPV infection by slot blot hybridization. Fifteen condyloma biopsy specimens were studied by Southern blot hybridization. RESULTS: Thirty-six cases (12.5%) with normal cervical cytology were HP V positive. The predominant HPV type in women with normal cytology is HPV-16. Risk factors for HPV infection in women with normal cytology depend on age and history of pregnancies. Twelve cases (80%) of condyloma contained HP V-6 or-11 sequences. The predominant HPV type in genital condyloma is HPV-11. CONCLUSIONS: HPV detection in population-based screening programs for cervical neoplasia can be an important tool in identifying women who are at risk of developing dysplasia and cervical cancer.

Original languageEnglish
Pages (from-to)39-45
Number of pages7
JournalInternational Journal of Gynecology and Obstetrics
Volume44
Issue number1
DOIs
StatePublished - 01 1994
Externally publishedYes

Keywords

  • Condyloma
  • HPV
  • Women with normal cytology

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