Abstract
OBJECTIVES: Identification and typing of HPV infections in genital condyloma and normal cytological cervix. METHODS: Cervical cells from 289 Pap cases with normal cytological findings were examined for HPV infection by slot blot hybridization. Fifteen condyloma biopsy specimens were studied by Southern blot hybridization. RESULTS: Thirty-six cases (12.5%) with normal cervical cytology were HP V positive. The predominant HPV type in women with normal cytology is HPV-16. Risk factors for HPV infection in women with normal cytology depend on age and history of pregnancies. Twelve cases (80%) of condyloma contained HP V-6 or-11 sequences. The predominant HPV type in genital condyloma is HPV-11. CONCLUSIONS: HPV detection in population-based screening programs for cervical neoplasia can be an important tool in identifying women who are at risk of developing dysplasia and cervical cancer.
Original language | English |
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Pages (from-to) | 39-45 |
Number of pages | 7 |
Journal | International Journal of Gynecology and Obstetrics |
Volume | 44 |
Issue number | 1 |
DOIs | |
State | Published - 01 1994 |
Externally published | Yes |
Keywords
- Condyloma
- HPV
- Women with normal cytology