Goodpasture's syndrome--a case report.

C. W. Yang*, C. C. Huang, S. Hsueh

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review


Goodpasture's syndrome is a disease characterized by diffuse pulmonary hemorrhage and glomerulonephritis with circulating anti-glomerular basement membrane antibody (anti-GBM antibody). Although it is reported in the western world, it is rarely diagnosed in Taiwan. We report a 26-year-old male admitted due to pulmonary hemorrhage and rapid progressive glomerulonephritis. Renal biopsy showed diffuse glomerular proliferation and 90% crescent formation, and immunofluorescence stain showed diffuse linear staining of IgG, C3, IgA, IgM along glomerular basement membranes and tubular basement membranes. He was treated with immunosuppressive agents. Pulmonary hemorrhage improved rapidly, but his renal function was severely impaired and he remained dialysis dependent.

Original languageEnglish
Pages (from-to)143-151
Number of pages9
JournalChang Gung Medical Journal
Issue number2
StatePublished - 20 06 1990
Externally publishedYes


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