Hepatic Resection in 120 Patients With Hepatocellular Carcinoma

Miin Chen, Tsann Long Hwang, Long Bin Benjamin Jeng, Yin Jan, Chia Siu Wang, Fong Chou

Research output: Contribution to journalJournal Article peer-review

121 Scopus citations

Abstract

• During the 11-year period from 1977 through 1987, hepatic resections were carried out in 120 patients with hepatocellular carcinoma (HCC). Twenty-five had HCCs smaller than 5 cm in diameter. There were 97 male and 23 female patients, with an average age of 51.5 years. Among them, 45.8% had liver cirrhosis and 80.8% were positive for hepatitis B surface antigen. Fourteen with ruptured HCCs underwent hepatic resection to control the intra-abdominal hemorrhage. Operative mortality within one month after surgery was 4.1%. The postoperative course was complicated by pleural effusion in 5.8%, subphrenic abscess in 2.5%, postoperative bleeding in 1.6%, hepatic failure in 1.6%, and bile leakage in 0.8% of the patients. The overall five-year survival rate in this series was 25.9%, while survival for the last five years was better (42.3% vs 11.9% for patients treated between 1977 and 1982). The cumulative survival rate had no relation to tumor rupture or liver cirrhosis. The group of patients with smaller tumors (diameter, < 5 cm) or without vascular invasion by tumor had better survival.

Original languageEnglish
Pages (from-to)1025-1028
Number of pages4
JournalArchives of Surgery
Volume124
Issue number9
DOIs
StatePublished - 09 1989
Externally publishedYes

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