TY - JOUR
T1 - Hepatocellular carcinoma associated with second primary malignancy
AU - Lin, Deng‐Yn ‐Y
AU - Liaw, Yun‐Fan ‐F
AU - Wu, Cheng‐Shyong ‐S
AU - Chang‐Chien, Chi‐Sin ‐S
AU - Chen, Pang‐Chi ‐C
AU - Chen, Tong‐Jong ‐J
PY - 1987/4
Y1 - 1987/4
N2 - ABSTRACT— In a consecutive series of 562 patients with pathologically documented hepatocellular carcinoma (HCC), 12 patients (2.1%) were found to have a second primary malignancy elsewhere. Of these, eight were male, four female, with ages ranging from 49 to 76 years (mean 60.7 ± 9.3 years). The associated cancers included eight cases of gastric cancers, an esophageal cancer, a stump cancer, a case of myelocytic leukemia and a histiocytic lymphoma. Eight cases had both malignancies diagnosed at the same admission. In the other four, HCC were detected after an interval of 4, 10, 12 and 39 months. Two had received previous chemotherapy or radiotherapy. Fifty percent of the 12 patients were hepatitis B surface antigen (HBsAg) positive. Their liver function tests and alpha‐fetoprotein levels were consistent with those of patients with HCC alone. The results suggest that the occurrence of HCC concomitant with or arising after another primary malignancy in Taiwan is not rare.
AB - ABSTRACT— In a consecutive series of 562 patients with pathologically documented hepatocellular carcinoma (HCC), 12 patients (2.1%) were found to have a second primary malignancy elsewhere. Of these, eight were male, four female, with ages ranging from 49 to 76 years (mean 60.7 ± 9.3 years). The associated cancers included eight cases of gastric cancers, an esophageal cancer, a stump cancer, a case of myelocytic leukemia and a histiocytic lymphoma. Eight cases had both malignancies diagnosed at the same admission. In the other four, HCC were detected after an interval of 4, 10, 12 and 39 months. Two had received previous chemotherapy or radiotherapy. Fifty percent of the 12 patients were hepatitis B surface antigen (HBsAg) positive. Their liver function tests and alpha‐fetoprotein levels were consistent with those of patients with HCC alone. The results suggest that the occurrence of HCC concomitant with or arising after another primary malignancy in Taiwan is not rare.
KW - hepatocellular carcinoma
KW - second primary malignancy
UR - https://www.scopus.com/pages/publications/0023254045
U2 - 10.1111/j.1600-0676.1987.tb00325.x
DO - 10.1111/j.1600-0676.1987.tb00325.x
M3 - 文章
C2 - 3039283
AN - SCOPUS:0023254045
SN - 0106-9543
VL - 7
SP - 106
EP - 109
JO - Liver
JF - Liver
IS - 2
ER -
