High prevalence of cagA- and babA2-positive Helicobacter pylori clinical isolates in Taiwan

Chih Ho Lai; Chun Hsien Kuo; Ya Chi Chen; Fang Yu Chao; Sek Kwong Poon; Chi Sen Chang; Wen Ching Wang

doi:10.1128/JCM.40.10.3860-3862.2002

High prevalence of cagA- and babA2-positive Helicobacter pylori clinical isolates in Taiwan

Chih Ho Lai, Chun Hsien Kuo, Ya Chi Chen, Fang Yu Chao, Sek Kwong Poon, Chi Sen Chang, Wen Ching Wang^*

^*Corresponding author for this work

National Tsing Hua University

Research output: Contribution to journal › Journal Article › peer-review

53 Scopus citations

Abstract

Two virulence markers, cagA and babA2, were characterized by PCR in 101 Helicobacter pylori isolates from a population in Taiwan. cagA was detected in 99% of the isolates, while babA2 was present in all of the isolates. Base deletions and substitutions at the forward babA2 primer annealing sites were found. Given their high prevalence, cagA and babA2 cannot be useful markers for predicting the high-risk patients of H. pylori infection in Taiwan.

Original language	English
Pages (from-to)	3860-3862
Number of pages	3
Journal	Journal of Clinical Microbiology
Volume	40
Issue number	10
DOIs	https://doi.org/10.1128/JCM.40.10.3860-3862.2002
State	Published - 01 10 2002
Externally published	Yes

Access to Document

10.1128/JCM.40.10.3860-3862.2002

Cite this

@article{bf22cf40a36d447292cc143af3b28d49,

title = "High prevalence of cagA- and babA2-positive Helicobacter pylori clinical isolates in Taiwan",

abstract = "Two virulence markers, cagA and babA2, were characterized by PCR in 101 Helicobacter pylori isolates from a population in Taiwan. cagA was detected in 99% of the isolates, while babA2 was present in all of the isolates. Base deletions and substitutions at the forward babA2 primer annealing sites were found. Given their high prevalence, cagA and babA2 cannot be useful markers for predicting the high-risk patients of H. pylori infection in Taiwan.",

author = "Lai, {Chih Ho} and Kuo, {Chun Hsien} and Chen, {Ya Chi} and Chao, {Fang Yu} and Poon, {Sek Kwong} and Chang, {Chi Sen} and Wang, {Wen Ching}",

year = "2002",

month = oct,

day = "1",

doi = "10.1128/JCM.40.10.3860-3862.2002",

language = "英语",

volume = "40",

pages = "3860--3862",

journal = "Journal of Clinical Microbiology",

issn = "0095-1137",

publisher = "American Society for Microbiology",

number = "10",

}

TY - JOUR

T1 - High prevalence of cagA- and babA2-positive Helicobacter pylori clinical isolates in Taiwan

AU - Lai, Chih Ho

AU - Kuo, Chun Hsien

AU - Chen, Ya Chi

AU - Chao, Fang Yu

AU - Poon, Sek Kwong

AU - Chang, Chi Sen

AU - Wang, Wen Ching

PY - 2002/10/1

Y1 - 2002/10/1

N2 - Two virulence markers, cagA and babA2, were characterized by PCR in 101 Helicobacter pylori isolates from a population in Taiwan. cagA was detected in 99% of the isolates, while babA2 was present in all of the isolates. Base deletions and substitutions at the forward babA2 primer annealing sites were found. Given their high prevalence, cagA and babA2 cannot be useful markers for predicting the high-risk patients of H. pylori infection in Taiwan.

AB - Two virulence markers, cagA and babA2, were characterized by PCR in 101 Helicobacter pylori isolates from a population in Taiwan. cagA was detected in 99% of the isolates, while babA2 was present in all of the isolates. Base deletions and substitutions at the forward babA2 primer annealing sites were found. Given their high prevalence, cagA and babA2 cannot be useful markers for predicting the high-risk patients of H. pylori infection in Taiwan.

UR - http://www.scopus.com/inward/record.url?scp=0036791089&partnerID=8YFLogxK

U2 - 10.1128/JCM.40.10.3860-3862.2002

DO - 10.1128/JCM.40.10.3860-3862.2002

M3 - 文章

C2 - 12354901

AN - SCOPUS:0036791089

SN - 0095-1137

VL - 40

SP - 3860

EP - 3862

JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

IS - 10

ER -

High prevalence of cagA- and babA2-positive Helicobacter pylori clinical isolates in Taiwan

Abstract

Access to Document

Other files and links

Fingerprint

Cite this