TY - JOUR
T1 - Histiocytoid hemangioma of the heart with peripheral eosinophilia
AU - Kuo, Tseng‐Tong ‐T
AU - Hsueh, Swei
AU - Su, Ih‐Jen ‐J
AU - Chen, Jong‐Shuin ‐S
AU - Gonzalez‐Crussi, Frank
PY - 1985/6/15
Y1 - 1985/6/15
N2 - A histiocytoid hemangioma of the heart is reported, which was found incidentally in a man with unusually high eosinophilia. The eosinophilia subsided dramatically following removal of the tumor. The “histiocytoid” or the “epithelioid” appearance of the tumor cells and the presence of vacuolated cells were the characteristic microscopic features. The endothelial origin of this tumor was verified by positive immunostaining for factor VIII‐related antigen and ultrastructural demonstration of intracytoplasmic lumen formation, abundant cytoplasmic filaments, pinocytotic vesicles, and prominent basal lamina. The presence of mitotic activity, cellular pleomorphism, and tumor necrosis raised the possibility of its malignant potential. The occurrence of this tumor in the heart may be mistaken for a myxoma clinically and a metastatic carcinoma pathologically.
AB - A histiocytoid hemangioma of the heart is reported, which was found incidentally in a man with unusually high eosinophilia. The eosinophilia subsided dramatically following removal of the tumor. The “histiocytoid” or the “epithelioid” appearance of the tumor cells and the presence of vacuolated cells were the characteristic microscopic features. The endothelial origin of this tumor was verified by positive immunostaining for factor VIII‐related antigen and ultrastructural demonstration of intracytoplasmic lumen formation, abundant cytoplasmic filaments, pinocytotic vesicles, and prominent basal lamina. The presence of mitotic activity, cellular pleomorphism, and tumor necrosis raised the possibility of its malignant potential. The occurrence of this tumor in the heart may be mistaken for a myxoma clinically and a metastatic carcinoma pathologically.
UR - http://www.scopus.com/inward/record.url?scp=0021814113&partnerID=8YFLogxK
U2 - 10.1002/1097-0142(19850615)55:12<2854::AID-CNCR2820551225>3.0.CO;2-F
DO - 10.1002/1097-0142(19850615)55:12<2854::AID-CNCR2820551225>3.0.CO;2-F
M3 - 文章
C2 - 2581685
AN - SCOPUS:0021814113
SN - 0008-543X
VL - 55
SP - 2854
EP - 2861
JO - Cancer
JF - Cancer
IS - 12
ER -