How Epstein Barr Virus Causes Lymphomas

Ya Fang Chiu; Khongpon Ponlachantra; Bill Sugden

doi:10.3390/v16111744

How Epstein Barr Virus Causes Lymphomas

Ya Fang Chiu, Khongpon Ponlachantra, Bill Sugden^*

^*Corresponding author for this work

Department of Microbiology and Immunology

Research output: Contribution to journal › Review article › peer-review

Abstract

Since Epstein–Barr Virus (EBV) was isolated 60 years ago, it has been studied clinically, epidemiologically, immunologically, and molecularly in the ensuing years. These combined studies allow a broad mechanistic understanding of how this ubiquitous human pathogen which infects more than 90% of adults can rarely cause multiple types of lymphomas. We survey these findings to provide a coherent description of its oncogenesis.

Original language	English
Article number	1744
Journal	Viruses
Volume	16
Issue number	11
DOIs	https://doi.org/10.3390/v16111744
State	Published - 06 11 2024

Bibliographical note

Publisher Copyright:
© 2024 by the authors.

Keywords

EBV
lymphomas
Lymphoma/virology
Animals
Humans
Carcinogenesis
Herpesvirus 4, Human/genetics
Epstein-Barr Virus Infections/virology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3390/v16111744

Cite this

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abstract = "Since Epstein–Barr Virus (EBV) was isolated 60 years ago, it has been studied clinically, epidemiologically, immunologically, and molecularly in the ensuing years. These combined studies allow a broad mechanistic understanding of how this ubiquitous human pathogen which infects more than 90% of adults can rarely cause multiple types of lymphomas. We survey these findings to provide a coherent description of its oncogenesis.",

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AB - Since Epstein–Barr Virus (EBV) was isolated 60 years ago, it has been studied clinically, epidemiologically, immunologically, and molecularly in the ensuing years. These combined studies allow a broad mechanistic understanding of how this ubiquitous human pathogen which infects more than 90% of adults can rarely cause multiple types of lymphomas. We survey these findings to provide a coherent description of its oncogenesis.

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KW - lymphomas

KW - Lymphoma/virology

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KW - Humans

KW - Carcinogenesis

KW - Herpesvirus 4, Human/genetics

KW - Epstein-Barr Virus Infections/virology

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JO - Viruses

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ER -

How Epstein Barr Virus Causes Lymphomas

Abstract

Bibliographical note

Keywords

UN SDGs

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