How Epstein Barr Virus Causes Lymphomas

Ya Fang Chiu; Khongpon Ponlachantra; Bill Sugden

doi:10.3390/v16111744

How Epstein Barr Virus Causes Lymphomas

Ya Fang Chiu
, Khongpon Ponlachantra
, Bill Sugden^*

^*Corresponding author for this work

Department of Microbiology and Immunology

Vidyasirimedhi Institute of Science and Technology
University of Wisconsin-Madison

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

Abstract

Since Epstein–Barr Virus (EBV) was isolated 60 years ago, it has been studied clinically, epidemiologically, immunologically, and molecularly in the ensuing years. These combined studies allow a broad mechanistic understanding of how this ubiquitous human pathogen which infects more than 90% of adults can rarely cause multiple types of lymphomas. We survey these findings to provide a coherent description of its oncogenesis.

Original language	English
Article number	1744
Journal	Viruses
Volume	16
Issue number	11
DOIs	https://doi.org/10.3390/v16111744
State	Published - 06 11 2024

Bibliographical note

Publisher Copyright:
© 2024 by the authors.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

EBV
lymphomas
Lymphoma/virology
Animals
Humans
Carcinogenesis
Herpesvirus 4, Human/genetics
Epstein-Barr Virus Infections/virology

Access to Document

10.3390/v16111744

Cite this

@article{951d23e8cb4946b6bd7770752882253b,

title = "How Epstein Barr Virus Causes Lymphomas",

abstract = "Since Epstein–Barr Virus (EBV) was isolated 60 years ago, it has been studied clinically, epidemiologically, immunologically, and molecularly in the ensuing years. These combined studies allow a broad mechanistic understanding of how this ubiquitous human pathogen which infects more than 90\% of adults can rarely cause multiple types of lymphomas. We survey these findings to provide a coherent description of its oncogenesis.",

keywords = "EBV, lymphomas, Lymphoma/virology, Animals, Humans, Carcinogenesis, Herpesvirus 4, Human/genetics, Epstein-Barr Virus Infections/virology",

author = "Chiu, \{Ya Fang\} and Khongpon Ponlachantra and Bill Sugden",

note = "Publisher Copyright: {\textcopyright} 2024 by the authors.",

year = "2024",

month = nov,

day = "6",

doi = "10.3390/v16111744",

language = "英语",

volume = "16",

journal = "Viruses",

issn = "1999-4915",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "11",

}

TY - JOUR

T1 - How Epstein Barr Virus Causes Lymphomas

AU - Chiu, Ya Fang

AU - Ponlachantra, Khongpon

AU - Sugden, Bill

PY - 2024/11/6

Y1 - 2024/11/6

N2 - Since Epstein–Barr Virus (EBV) was isolated 60 years ago, it has been studied clinically, epidemiologically, immunologically, and molecularly in the ensuing years. These combined studies allow a broad mechanistic understanding of how this ubiquitous human pathogen which infects more than 90% of adults can rarely cause multiple types of lymphomas. We survey these findings to provide a coherent description of its oncogenesis.

AB - Since Epstein–Barr Virus (EBV) was isolated 60 years ago, it has been studied clinically, epidemiologically, immunologically, and molecularly in the ensuing years. These combined studies allow a broad mechanistic understanding of how this ubiquitous human pathogen which infects more than 90% of adults can rarely cause multiple types of lymphomas. We survey these findings to provide a coherent description of its oncogenesis.

KW - EBV

KW - lymphomas

KW - Lymphoma/virology

KW - Animals

KW - Humans

KW - Carcinogenesis

KW - Herpesvirus 4, Human/genetics

KW - Epstein-Barr Virus Infections/virology

UR - https://www.scopus.com/pages/publications/85210452687

U2 - 10.3390/v16111744

DO - 10.3390/v16111744

M3 - 文献综述

C2 - 39599857

AN - SCOPUS:85210452687

SN - 1999-4915

VL - 16

JO - Viruses

JF - Viruses

IS - 11

M1 - 1744

ER -

How Epstein Barr Virus Causes Lymphomas

Abstract

Bibliographical note

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this