How killer cells kill.

J. D. Young*, Z. A. Cohn

*Corresponding author for this work

    Research output: Contribution to journalReview articlepeer-review

    25 Scopus citations

    Abstract

    Killer lymphocytes, the commandos of the immune system, attack tumor cells and cells infected by viruses. They kill by secreting protein molecules that link to form pores in target cells; the cells promptly leak to death. Study of the process may make it possible to improve the killers' efficiency in fighting cancer and such viral infections as AIDS.

    Original languageEnglish
    Pages (from-to)38-44
    Number of pages7
    JournalScientific American
    Volume258
    Issue number1
    DOIs
    StatePublished - 01 1988

    Keywords

    • Animal
    • Cell Membrane Permeability
    • Cytoplasmic Granules
    • Human
    • Killer Cells, Natural
    • Membrane Proteins
    • T-Lymphocytes, Cytotoxic

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