How killer cells kill.

J. D. Young; Z. A. Cohn

doi:10.1038/scientificamerican0188-38

How killer cells kill.

J. D. Young^*
, Z. A. Cohn

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

26 Scopus citations

Abstract

Killer lymphocytes, the commandos of the immune system, attack tumor cells and cells infected by viruses. They kill by secreting protein molecules that link to form pores in target cells; the cells promptly leak to death. Study of the process may make it possible to improve the killers' efficiency in fighting cancer and such viral infections as AIDS.

Original language	English
Pages (from-to)	38-44
Number of pages	7
Journal	Scientific American
Volume	258
Issue number	1
DOIs	https://doi.org/10.1038/scientificamerican0188-38
State	Published - 01 1988

Keywords

Animal
Cell Membrane Permeability
Cytoplasmic Granules
Human
Killer Cells, Natural
Membrane Proteins
T-Lymphocytes, Cytotoxic

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/scientificamerican0188-38

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title = "How killer cells kill.",

abstract = "Killer lymphocytes, the commandos of the immune system, attack tumor cells and cells infected by viruses. They kill by secreting protein molecules that link to form pores in target cells; the cells promptly leak to death. Study of the process may make it possible to improve the killers' efficiency in fighting cancer and such viral infections as AIDS.",

keywords = "Animal, Cell Membrane Permeability, Cytoplasmic Granules, Human, Killer Cells, Natural, Membrane Proteins, T-Lymphocytes, Cytotoxic",

author = "Young, \{J. D.\} and Cohn, \{Z. A.\}",

year = "1988",

month = jan,

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AU - Young, J. D.

AU - Cohn, Z. A.

PY - 1988/1

Y1 - 1988/1

N2 - Killer lymphocytes, the commandos of the immune system, attack tumor cells and cells infected by viruses. They kill by secreting protein molecules that link to form pores in target cells; the cells promptly leak to death. Study of the process may make it possible to improve the killers' efficiency in fighting cancer and such viral infections as AIDS.

AB - Killer lymphocytes, the commandos of the immune system, attack tumor cells and cells infected by viruses. They kill by secreting protein molecules that link to form pores in target cells; the cells promptly leak to death. Study of the process may make it possible to improve the killers' efficiency in fighting cancer and such viral infections as AIDS.

KW - Animal

KW - Cell Membrane Permeability

KW - Cytoplasmic Granules

KW - Human

KW - Killer Cells, Natural

KW - Membrane Proteins

KW - T-Lymphocytes, Cytotoxic

UR - https://www.scopus.com/pages/publications/0023781007

U2 - 10.1038/scientificamerican0188-38

DO - 10.1038/scientificamerican0188-38

M3 - 文献综述

C2 - 3051347

AN - SCOPUS:0023781007

SN - 0036-8733

VL - 258

SP - 38

EP - 44

JO - Scientific American

JF - Scientific American

IS - 1

ER -

How killer cells kill.

Abstract

Keywords

UN SDGs

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