Skip to main navigation Skip to search Skip to main content

Imaging properties of gold nanoparticles: CT number dependence study

  • Chang Gung University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

In recent years, there has been a rapid research progress of molecular imaging technology. Many investigations in molecular imaging such as the nanoparticle applications in targeted drug delivery have been widely studied in several key small animal models. Various nanoparticles used as either the drug delivery carriers, imaging contrast mediums or target-specific therapeutic agents have established a novel research platform for biomedical related scientists and clinicians. Among these nanoparticles, gold nanoparticles have the unique non-toxic and stability properties. In this work, a commercially-available micro CT imaging system was used to specifically study the imaging properties for 15 nm spherical-shaped gold particles. Imaging properties were quantified by the CT numbers obtained from a series of photon energy levels in the micro CT scanner. We also compared the imaging results between gold nanoparticles and iodinated contrast medium to study the potential impact of gold nanoparticles served as the contrast agent.

Original languageEnglish
Title of host publicationMedical Imaging 2010
Subtitle of host publicationPhysics of Medical Imaging
EditionPART 2
DOIs
StatePublished - 2010
EventMedical Imaging 2010: Physics of Medical Imaging - San Diego, CA, United States
Duration: 15 02 201018 02 2010

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
NumberPART 2
Volume7622
ISSN (Print)1605-7422

Conference

ConferenceMedical Imaging 2010: Physics of Medical Imaging
Country/TerritoryUnited States
CitySan Diego, CA
Period15/02/1018/02/10

Keywords

  • CT numbers
  • Cone beam CT
  • Contrast medium
  • Hounsfield Units
  • Micro CT
  • Molecular imaging
  • Nanoparticles
  • Small animals
  • Targeted drug delivery

Fingerprint

Dive into the research topics of 'Imaging properties of gold nanoparticles: CT number dependence study'. Together they form a unique fingerprint.

Cite this