Imaging serotonin transporters with i-adam brain spect in healthy non-human primates

Wen Sheng Huang; Kuo Hsing Ma; Cheng Yi Cheng; Cheng Yu Chen; Ying Kai Fu; Yuan Hwa Chou; Shiaw Pyng Wey; Jian Chuan Liu

doi:10.1097/00006231-200405000-00014

Imaging serotonin transporters with i-adam brain spect in healthy non-human primates

Wen Sheng Huang
, Kuo Hsing Ma
, Cheng Yi Cheng
, Cheng Yu Chen
, Ying Kai Fu
, Yuan Hwa Chou
, Shiaw Pyng Wey
, Jian Chuan Liu

Research output: Contribution to journal › Journal Article › peer-review

13 Scopus citations

Abstract

Serotonin transporters (SERTs) play a major role in modulating serotonergic neuronal function and are the target of many antidepressant drugs used in neuro-psychiatric disorders. To gain more information on the temporal distribution of SERTs, 2-([2-([dimethylamino]methyl)phenoxyl]thio)-5-[I]iodophenylamine (I-ADAM) single photon emission computed tomography (SPECT) was utilized in an in vivo imaging study using non-human primates.

Original language	English
Pages (from-to)	515-519
Number of pages	5
Journal	Nuclear Medicine Communications
Volume	25
Issue number	5
DOIs	https://doi.org/10.1097/00006231-200405000-00014
State	Published - 05 2004
Externally published	Yes

Keywords

Brain SPECT
I-ADAM
Non-human primate
Serotonin transporter

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10.1097/00006231-200405000-00014

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title = "Imaging serotonin transporters with i-adam brain spect in healthy non-human primates",

abstract = "Serotonin transporters (SERTs) play a major role in modulating serotonergic neuronal function and are the target of many antidepressant drugs used in neuro-psychiatric disorders. To gain more information on the temporal distribution of SERTs, 2-([2-([dimethylamino]methyl)phenoxyl]thio)-5-[I]iodophenylamine (I-ADAM) single photon emission computed tomography (SPECT) was utilized in an in vivo imaging study using non-human primates.",

keywords = "Brain SPECT, I-ADAM, Non-human primate, Serotonin transporter",

author = "Huang, \{Wen Sheng\} and Ma, \{Kuo Hsing\} and Cheng, \{Cheng Yi\} and Chen, \{Cheng Yu\} and Fu, \{Ying Kai\} and Chou, \{Yuan Hwa\} and Wey, \{Shiaw Pyng\} and Liu, \{Jian Chuan\}",

year = "2004",

month = may,

doi = "10.1097/00006231-200405000-00014",

language = "英语",

volume = "25",

pages = "515--519",

journal = "Nuclear Medicine Communications",

issn = "0143-3636",

publisher = "Lippincott Williams and Wilkins",

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}

TY - JOUR

T1 - Imaging serotonin transporters with i-adam brain spect in healthy non-human primates

AU - Huang, Wen Sheng

AU - Ma, Kuo Hsing

AU - Cheng, Cheng Yi

AU - Chen, Cheng Yu

AU - Fu, Ying Kai

AU - Chou, Yuan Hwa

AU - Wey, Shiaw Pyng

AU - Liu, Jian Chuan

PY - 2004/5

Y1 - 2004/5

N2 - Serotonin transporters (SERTs) play a major role in modulating serotonergic neuronal function and are the target of many antidepressant drugs used in neuro-psychiatric disorders. To gain more information on the temporal distribution of SERTs, 2-([2-([dimethylamino]methyl)phenoxyl]thio)-5-[I]iodophenylamine (I-ADAM) single photon emission computed tomography (SPECT) was utilized in an in vivo imaging study using non-human primates.

AB - Serotonin transporters (SERTs) play a major role in modulating serotonergic neuronal function and are the target of many antidepressant drugs used in neuro-psychiatric disorders. To gain more information on the temporal distribution of SERTs, 2-([2-([dimethylamino]methyl)phenoxyl]thio)-5-[I]iodophenylamine (I-ADAM) single photon emission computed tomography (SPECT) was utilized in an in vivo imaging study using non-human primates.

KW - Brain SPECT

KW - I-ADAM

KW - Non-human primate

KW - Serotonin transporter

UR - https://www.scopus.com/pages/publications/2342590028

U2 - 10.1097/00006231-200405000-00014

DO - 10.1097/00006231-200405000-00014

M3 - 文章

C2 - 15100512

AN - SCOPUS:2342590028

SN - 0143-3636

VL - 25

SP - 515

EP - 519

JO - Nuclear Medicine Communications

JF - Nuclear Medicine Communications

IS - 5

ER -

Imaging serotonin transporters with i-adam brain spect in healthy non-human primates

Abstract

Keywords

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