Abstract
Imaging serotonin transporters during antidepressant treatment in small animals is a useful tool for preclinical study during drug development. In this work, we aimed to demonstrate the feasibility of using I-ADAM and small-animal SPECT to monitor serotonin transporter availabilities in rat brains prior to and after administration of a selective serotonin re-uptake inhibitor.
Original language | English |
---|---|
Pages (from-to) | 615-621 |
Number of pages | 7 |
Journal | Nuclear Medicine Communications |
Volume | 28 |
Issue number | 8 |
DOIs | |
State | Published - 08 2007 |
Externally published | Yes |
Keywords
- Serotonin transporter
- Small-animal SPECT