Impact of rotavirus vaccination on rotavirus hospitalizations in Taiwanese children

Rachel M. Burke, Shuman Shih, Chao Agnes Hsiung, Catherine Yen, Baoming Jiang, Umesh D. Parashar, Jacqueline E. Tate, Fang Tzy Wu*, Yhu Chering Huang

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

1 Scopus citations


In 2006, two rotavirus vaccines were licensed in Taiwan but were not added to the national immunization schedule. National Health Insurance data from 2003 through 2017 were used to compare rotavirus-associated pediatric hospitalizations before and after vaccine introduction. Rotavirus hospitalization rates among children < 5 years of age significantly declined by 24% (95% confidence interval [CI] 23 – 25%) in post-vaccine compared to pre-vaccine rotavirus seasons. Rotavirus hospitalization rates declined by 42% (95% CI 39 – 44%) among infants < 12 months of age, and by 38% (95% CI 36 – 40%) among children 12 – 23 months of age. These findings suggest that, despite not being included in the national immunization schedule, rotavirus vaccines had a measurable impact on reducing rotavirus hospitalization burden among Taiwanese children.

Original languageEnglish
Pages (from-to)7135-7139
Number of pages5
Issue number49
StatePublished - 03 12 2021

Bibliographical note

Publisher Copyright:
© 2021


  • Acute gastroenteritis
  • Pediatric gastroenteritis
  • Rotavirus
  • Rotavirus vaccine
  • Vaccine impact


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