Impact of the COVID-19 pandemic on inflammatory bowel disease care in Taiwan: A multicenter study

Yen Ling Peng; Chung Hsin Chang; Shu Chen Wei; Tien Yu Huang; Wei Chen Tai; Wen Hung Hsu; Deng Chyang Wu; Hsu Heng Yen; Chi Ming Tai; Chen Wang Chang; Wei Chen Lin; Horng Yuan Wang; Chun Chi Lin; Chia Jung Kuo; Cheng Tang Chiu; Ching Pin Lin; Hsi Chang Lee; Jia Feng Wu; Chen Shuan Chung

doi:10.1016/j.jfma.2023.03.017

Impact of the COVID-19 pandemic on inflammatory bowel disease care in Taiwan: A multicenter study

Yen Ling Peng
, Chung Hsin Chang
, Shu Chen Wei
, Tien Yu Huang
, Wei Chen Tai
, Wen Hung Hsu
, Deng Chyang Wu
, Hsu Heng Yen
, Chi Ming Tai
, Chen Wang Chang
, Wei Chen Lin
, Horng Yuan Wang
, Chun Chi Lin
, Chia Jung Kuo
, Cheng Tang Chiu
, Ching Pin Lin
, Hsi Chang Lee
, Jia Feng Wu
, Chen Shuan Chung^*

^*Corresponding author for this work

Far Eastern Memorial Hospital
Taiwan Society of Inflammatory Bowel Disease
Veterans General Hospital-Taichung Taiwan
National Taiwan University
Taiwan Association for the Study of Small Intestinal Diseases (TASSID)
Triservice General Hospital Taiwan
Chang Gung Memorial Hospital
Kaohsiung Medical University
Changhua Christian Hospital
I-Shou University
Mackay Memorial Hospital Taiwan
Mackay Medicine, Nursing and Management College Taiwan
Veterans General Hospital-Taipei
Chung Shan Medical University
Taipei City Hospital
Fu Jen Catholic University

Research output: Contribution to journal › Journal Article › peer-review

3 Scopus citations

Abstract

BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic had a great impact on healthcare system and patients. This study aimed to evaluate the effect of the COVID-19 pandemic on the perceptions of patients with inflammatory bowel disease (IBD).

METHODS: This prospective multicenter study was conducted between July 2021 and December 2021. Patients with IBD answered a structured questionnaire, and their degree of anxiety was assessed using a visual analogue scale (VAS) before and after reading educational materials.

RESULTS: A total of 225 (47.67%) patients with Crohn's disease, 244 (51.69%) with ulcerative colitis and 3 (0.64%) with indeterminate colitis were enrolled. Common concerns were adverse events from vaccination (20.34%), and higher risks of developing severe COVID-19 (19.28%) and COVID-19 infection (16.31%) than the general population. Medications deemed by the patients to increase the risk of COVID-19 were immunomodulators (16.10%), anti-tumor necrosis factor-α antagonists (9.96%), and corticosteroids (9.32%). Thirty-five (7.42%) patients self-discontinued IBD medication, of whom 12 (34.28%) had worse symptoms. Older age (>50 years) (OR 1.10, 95% CI 1.01-1.19, p = 0.03), IBD-related complications (OR 1.16, 95% CI 1.04-1.28, p = 0.01), education status below senior high school (OR 1.22, 95% CI 1.08-1.37, p = 0.001), and residing in north-central Taiwan (OR 1.21, 95% CI 1.10-1.34, p < 0.001) were associated with more anxiety. None of the enrolled patients contracted COVID-19. The anxiety VAS score (mean ± SD) improved after reading the educational materials (3.84 ± 2.33 vs. 2.81 ± 1.96, p < 0.001).

CONCLUSION: The medical behavior of IBD patients was influenced by the COVID-19 pandemic, and their anxiety could be mitigated after education.

Original language	English
Pages (from-to)	1042-1049
Number of pages	8
Journal	Journal of the Formosan Medical Association
Volume	122
Issue number	10
DOIs	https://doi.org/10.1016/j.jfma.2023.03.017
State	Published - 10 2023
Externally published	Yes

Bibliographical note

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

COVID-19
Inflammatory bowel disease
Patient education
SARS-CoV-2
Inflammatory Bowel Diseases/complications
COVID-19/epidemiology
Pandemics
Prospective Studies
Humans
Taiwan/epidemiology

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10.1016/j.jfma.2023.03.017

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Peng, Y. L., Chang, C. H., Wei, S. C., Huang, T. Y., Tai, W. C., Hsu, W. H., Wu, D. C., Yen, H. H., Tai, C. M., Chang, C. W., Lin, W. C., Wang, H. Y., Lin, C. C., Kuo, C. J., Chiu, C. T., Lin, C. P., Lee, H. C., Wu, J. F., & Chung, C. S. (2023). Impact of the COVID-19 pandemic on inflammatory bowel disease care in Taiwan: A multicenter study. Journal of the Formosan Medical Association, 122(10), 1042-1049. https://doi.org/10.1016/j.jfma.2023.03.017

@article{decc18f287344540abdf8fcd27dcf0e6,

title = "Impact of the COVID-19 pandemic on inflammatory bowel disease care in Taiwan: A multicenter study",

abstract = "BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic had a great impact on healthcare system and patients. This study aimed to evaluate the effect of the COVID-19 pandemic on the perceptions of patients with inflammatory bowel disease (IBD).METHODS: This prospective multicenter study was conducted between July 2021 and December 2021. Patients with IBD answered a structured questionnaire, and their degree of anxiety was assessed using a visual analogue scale (VAS) before and after reading educational materials.RESULTS: A total of 225 (47.67\%) patients with Crohn's disease, 244 (51.69\%) with ulcerative colitis and 3 (0.64\%) with indeterminate colitis were enrolled. Common concerns were adverse events from vaccination (20.34\%), and higher risks of developing severe COVID-19 (19.28\%) and COVID-19 infection (16.31\%) than the general population. Medications deemed by the patients to increase the risk of COVID-19 were immunomodulators (16.10\%), anti-tumor necrosis factor-α antagonists (9.96\%), and corticosteroids (9.32\%). Thirty-five (7.42\%) patients self-discontinued IBD medication, of whom 12 (34.28\%) had worse symptoms. Older age (>50 years) (OR 1.10, 95\% CI 1.01-1.19, p = 0.03), IBD-related complications (OR 1.16, 95\% CI 1.04-1.28, p = 0.01), education status below senior high school (OR 1.22, 95\% CI 1.08-1.37, p = 0.001), and residing in north-central Taiwan (OR 1.21, 95\% CI 1.10-1.34, p < 0.001) were associated with more anxiety. None of the enrolled patients contracted COVID-19. The anxiety VAS score (mean ± SD) improved after reading the educational materials (3.84 ± 2.33 vs. 2.81 ± 1.96, p < 0.001).CONCLUSION: The medical behavior of IBD patients was influenced by the COVID-19 pandemic, and their anxiety could be mitigated after education.",

keywords = "COVID-19, Inflammatory bowel disease, Patient education, SARS-CoV-2, Inflammatory Bowel Diseases/complications, COVID-19/epidemiology, Pandemics, Prospective Studies, Humans, Taiwan/epidemiology",

author = "Peng, \{Yen Ling\} and Chang, \{Chung Hsin\} and Wei, \{Shu Chen\} and Huang, \{Tien Yu\} and Tai, \{Wei Chen\} and Hsu, \{Wen Hung\} and Wu, \{Deng Chyang\} and Yen, \{Hsu Heng\} and Tai, \{Chi Ming\} and Chang, \{Chen Wang\} and Lin, \{Wei Chen\} and Wang, \{Horng Yuan\} and Lin, \{Chun Chi\} and Kuo, \{Chia Jung\} and Chiu, \{Cheng Tang\} and Lin, \{Ching Pin\} and Lee, \{Hsi Chang\} and Wu, \{Jia Feng\} and Chung, \{Chen Shuan\}",

year = "2023",

month = oct,

doi = "10.1016/j.jfma.2023.03.017",

language = "英语",

volume = "122",

pages = "1042--1049",

journal = "Journal of the Formosan Medical Association",

issn = "0929-6646",

publisher = "Elsevier B.V.",

number = "10",

}

Peng, YL, Chang, CH, Wei, SC, Huang, TY, Tai, WC, Hsu, WH, Wu, DC, Yen, HH, Tai, CM, Chang, CW, Lin, WC, Wang, HY, Lin, CC, Kuo, CJ, Chiu, CT, Lin, CP, Lee, HC, Wu, JF & Chung, CS 2023, 'Impact of the COVID-19 pandemic on inflammatory bowel disease care in Taiwan: A multicenter study', Journal of the Formosan Medical Association, vol. 122, no. 10, pp. 1042-1049. https://doi.org/10.1016/j.jfma.2023.03.017

TY - JOUR

T1 - Impact of the COVID-19 pandemic on inflammatory bowel disease care in Taiwan

T2 - A multicenter study

AU - Peng, Yen Ling

AU - Chang, Chung Hsin

AU - Wei, Shu Chen

AU - Huang, Tien Yu

AU - Tai, Wei Chen

AU - Hsu, Wen Hung

AU - Wu, Deng Chyang

AU - Yen, Hsu Heng

AU - Tai, Chi Ming

AU - Chang, Chen Wang

AU - Lin, Wei Chen

AU - Wang, Horng Yuan

AU - Lin, Chun Chi

AU - Kuo, Chia Jung

AU - Chiu, Cheng Tang

AU - Lin, Ching Pin

AU - Lee, Hsi Chang

AU - Wu, Jia Feng

AU - Chung, Chen Shuan

PY - 2023/10

Y1 - 2023/10

N2 - BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic had a great impact on healthcare system and patients. This study aimed to evaluate the effect of the COVID-19 pandemic on the perceptions of patients with inflammatory bowel disease (IBD).METHODS: This prospective multicenter study was conducted between July 2021 and December 2021. Patients with IBD answered a structured questionnaire, and their degree of anxiety was assessed using a visual analogue scale (VAS) before and after reading educational materials.RESULTS: A total of 225 (47.67%) patients with Crohn's disease, 244 (51.69%) with ulcerative colitis and 3 (0.64%) with indeterminate colitis were enrolled. Common concerns were adverse events from vaccination (20.34%), and higher risks of developing severe COVID-19 (19.28%) and COVID-19 infection (16.31%) than the general population. Medications deemed by the patients to increase the risk of COVID-19 were immunomodulators (16.10%), anti-tumor necrosis factor-α antagonists (9.96%), and corticosteroids (9.32%). Thirty-five (7.42%) patients self-discontinued IBD medication, of whom 12 (34.28%) had worse symptoms. Older age (>50 years) (OR 1.10, 95% CI 1.01-1.19, p = 0.03), IBD-related complications (OR 1.16, 95% CI 1.04-1.28, p = 0.01), education status below senior high school (OR 1.22, 95% CI 1.08-1.37, p = 0.001), and residing in north-central Taiwan (OR 1.21, 95% CI 1.10-1.34, p < 0.001) were associated with more anxiety. None of the enrolled patients contracted COVID-19. The anxiety VAS score (mean ± SD) improved after reading the educational materials (3.84 ± 2.33 vs. 2.81 ± 1.96, p < 0.001).CONCLUSION: The medical behavior of IBD patients was influenced by the COVID-19 pandemic, and their anxiety could be mitigated after education.

AB - BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic had a great impact on healthcare system and patients. This study aimed to evaluate the effect of the COVID-19 pandemic on the perceptions of patients with inflammatory bowel disease (IBD).METHODS: This prospective multicenter study was conducted between July 2021 and December 2021. Patients with IBD answered a structured questionnaire, and their degree of anxiety was assessed using a visual analogue scale (VAS) before and after reading educational materials.RESULTS: A total of 225 (47.67%) patients with Crohn's disease, 244 (51.69%) with ulcerative colitis and 3 (0.64%) with indeterminate colitis were enrolled. Common concerns were adverse events from vaccination (20.34%), and higher risks of developing severe COVID-19 (19.28%) and COVID-19 infection (16.31%) than the general population. Medications deemed by the patients to increase the risk of COVID-19 were immunomodulators (16.10%), anti-tumor necrosis factor-α antagonists (9.96%), and corticosteroids (9.32%). Thirty-five (7.42%) patients self-discontinued IBD medication, of whom 12 (34.28%) had worse symptoms. Older age (>50 years) (OR 1.10, 95% CI 1.01-1.19, p = 0.03), IBD-related complications (OR 1.16, 95% CI 1.04-1.28, p = 0.01), education status below senior high school (OR 1.22, 95% CI 1.08-1.37, p = 0.001), and residing in north-central Taiwan (OR 1.21, 95% CI 1.10-1.34, p < 0.001) were associated with more anxiety. None of the enrolled patients contracted COVID-19. The anxiety VAS score (mean ± SD) improved after reading the educational materials (3.84 ± 2.33 vs. 2.81 ± 1.96, p < 0.001).CONCLUSION: The medical behavior of IBD patients was influenced by the COVID-19 pandemic, and their anxiety could be mitigated after education.

KW - COVID-19

KW - Inflammatory bowel disease

KW - Patient education

KW - SARS-CoV-2

KW - Inflammatory Bowel Diseases/complications

KW - COVID-19/epidemiology

KW - Pandemics

KW - Prospective Studies

KW - Humans

KW - Taiwan/epidemiology

UR - https://www.scopus.com/pages/publications/85151572816

U2 - 10.1016/j.jfma.2023.03.017

DO - 10.1016/j.jfma.2023.03.017

M3 - 文章

C2 - 37019722

AN - SCOPUS:85151572816

SN - 0929-6646

VL - 122

SP - 1042

EP - 1049

JO - Journal of the Formosan Medical Association

JF - Journal of the Formosan Medical Association

IS - 10

ER -

Impact of the COVID-19 pandemic on inflammatory bowel disease care in Taiwan: A multicenter study

Abstract

Bibliographical note

UN SDGs

Keywords

Access to Document

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