TY - JOUR
T1 - Improvement in left ventricular function following coronary stenting in patients with acute myocardial infarction
T2 - 6-month and 3-year follow-up
AU - Hsieh, I. Chang
AU - Huang, Hsuan Li
AU - See, Lai Chu
AU - Chang, Shang Hung
AU - Chang, Hern Jia
AU - Hung, Kuo Chun
AU - Lin, Fun Chung
AU - Wu, Delon
PY - 2006/8/10
Y1 - 2006/8/10
N2 - Background: This study assesses hemodynamic and angiographic changes in patients with a patent infarct-related artery (IRA) after acute myocardial infarction (AMI). Methods: One hundred and seventy-seven patients with first AMI, who received a predischarge stenting to the IRA and sustained a patent IRA over 3 years, were stratified into 3 groups according to the baseline left ventricular ejection fraction (LVEF): group A included 63 patients with a LVEF of > 49%, group B 73 patients with a LVEF of 40%-49%, and group C 41 patients with a LVEF of < 40%. The hemodynamic and angiographic parameters were compared at baseline, 6-month and 3-year follow-up. Results: The LV end-diastolic volume index increased 1, 4 and 4 ml/m2 at 6 months and 4, 5 and 10 ml/m2 at 3 years, respectively in group A, B and C. The LVEF increased 4%, 7% and 12% at 6 months and 6%, 8% and 14% at 3 years, respectively in group A, B and C. The stroke volume index increased 3, 7 and 12 ml/m2 at 6 months and 6, 8 and 15 ml/m2 at 3 years, respectively in group A, B and C. The LV wall motion score decreased 2, 3 and 3 at 6 months and was unchanged at 3 years, respectively in group A, B and C. The LV end-diastolic pressure decreased 2, 3 and 4 mm Hg, respectively in group A, B and C, at 6-month follow-up and remained stable at 3 years. Conclusions: Long-term beneficial effects in patients receiving a late predischarge intracoronary stenting following first AMI were seen and these may be related to patent IRA. A progressive improvement in left ventricular remodeling occurs in all patients regardless of their initial left ventricular function and the improvement continues for at least 3 years.
AB - Background: This study assesses hemodynamic and angiographic changes in patients with a patent infarct-related artery (IRA) after acute myocardial infarction (AMI). Methods: One hundred and seventy-seven patients with first AMI, who received a predischarge stenting to the IRA and sustained a patent IRA over 3 years, were stratified into 3 groups according to the baseline left ventricular ejection fraction (LVEF): group A included 63 patients with a LVEF of > 49%, group B 73 patients with a LVEF of 40%-49%, and group C 41 patients with a LVEF of < 40%. The hemodynamic and angiographic parameters were compared at baseline, 6-month and 3-year follow-up. Results: The LV end-diastolic volume index increased 1, 4 and 4 ml/m2 at 6 months and 4, 5 and 10 ml/m2 at 3 years, respectively in group A, B and C. The LVEF increased 4%, 7% and 12% at 6 months and 6%, 8% and 14% at 3 years, respectively in group A, B and C. The stroke volume index increased 3, 7 and 12 ml/m2 at 6 months and 6, 8 and 15 ml/m2 at 3 years, respectively in group A, B and C. The LV wall motion score decreased 2, 3 and 3 at 6 months and was unchanged at 3 years, respectively in group A, B and C. The LV end-diastolic pressure decreased 2, 3 and 4 mm Hg, respectively in group A, B and C, at 6-month follow-up and remained stable at 3 years. Conclusions: Long-term beneficial effects in patients receiving a late predischarge intracoronary stenting following first AMI were seen and these may be related to patent IRA. A progressive improvement in left ventricular remodeling occurs in all patients regardless of their initial left ventricular function and the improvement continues for at least 3 years.
KW - Left ventricular function
KW - Myocardial infarction
KW - Stents and stenting
UR - http://www.scopus.com/inward/record.url?scp=33746284319&partnerID=8YFLogxK
U2 - 10.1016/j.ijcard.2005.07.005
DO - 10.1016/j.ijcard.2005.07.005
M3 - 文章
C2 - 16188332
AN - SCOPUS:33746284319
SN - 0167-5273
VL - 111
SP - 209
EP - 216
JO - International Journal of Cardiology
JF - International Journal of Cardiology
IS - 2
ER -