Abstract
In vitro cell culture device was developed for the investigation of inhibition effect of cell colonies using alternating electric field. Cancer cells were cultured in 3D hydrogel and cell colonies, or called tumor spheroids, were gradually formed in the culture device. During the culture course, alternating electric field was applied and the conditions were investigated to optimize the inhibition effect of cell colonies. Results showed that electric field at frequency of 130 kHz and 0.5 Vpp was the minimal effective conditions of the inhibition of cell colonies. The device was demonstrated to provide a practical tool for the investigation of the efficacy and the therapeutic conditions of inhibiting tumors.
| Original language | English |
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| Title of host publication | 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society |
| Subtitle of host publication | Smarter Technology for a Healthier World, EMBC 2017 - Proceedings |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| Pages | 2060-2063 |
| Number of pages | 4 |
| ISBN (Electronic) | 9781509028092 |
| DOIs | |
| State | Published - 13 09 2017 |
| Event | 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017 - Jeju Island, Korea, Republic of Duration: 11 07 2017 → 15 07 2017 |
Publication series
| Name | Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS |
|---|---|
| ISSN (Print) | 1557-170X |
Conference
| Conference | 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017 |
|---|---|
| Country/Territory | Korea, Republic of |
| City | Jeju Island |
| Period | 11/07/17 → 15/07/17 |
Bibliographical note
Publisher Copyright:© 2017 IEEE.
