TY - JOUR
T1 - Incidence and Risk of Carpal Tunnel Syndrome in End-Stage Renal Disease Patients on Dialysis
T2 - A Nationwide Population-Based Matched Cohort Study
AU - Tsai, Chia Hsuan
AU - Hsu, Hsiang Hao
AU - Chen, Shih Heng
AU - Chien, Ling
AU - Lin, Jennifer An Jou
AU - Chang, Chee Jen
AU - Kao, Huang Kai
N1 - Publisher Copyright:
© Wolters Kluwer Health, Inc. All rights reserved.
PY - 2020/1/1
Y1 - 2020/1/1
N2 - Carpal tunnel syndrome (CTS) is a common cause of compression neuropathy of the upper extremities. This retrospective nationwide matched cohort study was conducted using the data from the Taiwan National Health Insurance Research Database between January 2003 and December 2012. The incidence rate of CTS was 975.84 and 544.12/100,000 person-years, respectively, yielding an incidence rate ratio of 1.79 (95% confidence interval, 1.68-1.91, P < 0.0001). CTS patients with End-stage renal disease (ESRD) in the dialysis group were more likely to receive surgical intervention than those the control group (62.41% vs 12.89%, P < 0.0001). The risk of CTS was significantly higher in the ESRD on dialysis cohort (10-year cumulative incidence, 8.0%) than in the control cohort (5.1%), which yielded an adjusted hazard ratio of 13.95 (95% confidence interval, 10.95-17.76, P < 0.0001). The high risk of CTS in ESRD patients on dialysis suggests that timely referral to hand surgeons with appropriate treatment should prevent permanent median nerve damage by CTS and may possibly improve patients' quality of life.
AB - Carpal tunnel syndrome (CTS) is a common cause of compression neuropathy of the upper extremities. This retrospective nationwide matched cohort study was conducted using the data from the Taiwan National Health Insurance Research Database between January 2003 and December 2012. The incidence rate of CTS was 975.84 and 544.12/100,000 person-years, respectively, yielding an incidence rate ratio of 1.79 (95% confidence interval, 1.68-1.91, P < 0.0001). CTS patients with End-stage renal disease (ESRD) in the dialysis group were more likely to receive surgical intervention than those the control group (62.41% vs 12.89%, P < 0.0001). The risk of CTS was significantly higher in the ESRD on dialysis cohort (10-year cumulative incidence, 8.0%) than in the control cohort (5.1%), which yielded an adjusted hazard ratio of 13.95 (95% confidence interval, 10.95-17.76, P < 0.0001). The high risk of CTS in ESRD patients on dialysis suggests that timely referral to hand surgeons with appropriate treatment should prevent permanent median nerve damage by CTS and may possibly improve patients' quality of life.
KW - carpal tunnel syndrome
KW - dialysis
KW - end-stage renal disease
UR - https://www.scopus.com/pages/publications/85076483841
U2 - 10.1097/SAP.0000000000002181
DO - 10.1097/SAP.0000000000002181
M3 - 文章
C2 - 31833895
AN - SCOPUS:85076483841
SN - 0148-7043
VL - 84
SP - S100-S106
JO - Annals of Plastic Surgery
JF - Annals of Plastic Surgery
IS - 1
ER -