Incidence of subsequent hip fractures is significantly increased within the first month after distal radius fracture in patients older than 60 years

Chia Wen Chen, Teng Le Huang, Li Ting Su, Yu Cheng Kuo, Sai Chuen Wu, Chi Yuan Li, Kuen Bao Chen, Fung Chang Sung*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

45 Scopus citations


BACKGROUND: Distal radius fracture is recognized as an osteoporosis-related fracture in aged population. If another osteoporosis-related fracture occurs in a short period, it represents a prolonged hospitalization and a considerable economic burden to the society. We evaluated the relationship between distal radius fracture and subsequent hip fracture within 1 year, especially in the critical time and age. METHODS: We identified newly diagnosed distal radius fracture patients in 2000 to 2006 as an exposed cohort (N = 9,986). A comparison cohort (N = 81,227) was randomly selected from patients without distal radius fracture in the same year of exposed cohort. The subjects were followed up for 1 year since the recruited date.We compared the sociodemographic factors between two cohorts. Furthermore, the time interval following the previous distal radial fracture and the incidence of subsequent hip fracture was studied in detail. RESULTS: The incidence of hip fracture within 1 year increased with age in both cohorts. The risk was 5.67 times (84.6 vs. 14.9 per 10,000 person-years) greater in the distal radial fracture cohort than in the comparison cohort. The multivariate Cox proportional hazard regression analyses showed the hazard ratios of hip fracture in relation to distal radial fracturewas 3.45 (95% confidence interval = 2.59-4.61). The highest incidence was within the first month after distal radial fracture, 17-fold higher than the comparison cohort (17.9 vs. 1.05 per 10,000). Among comorbidities, age 9 60 years was also a significant factor associated with hip fracture (hazard ratio = 8.67, 95% confidence interval = 4.51-16.7). CONCLUSIONS: Patients with distal radius fracture and age >60 yearswill significantly increase the incidence of subsequent hip fracture, especially within the first month. LEVEL OF EVIDENCE: Prognostic/epidemiologic study, level II.

Original languageEnglish
Pages (from-to)317-321
Number of pages5
JournalJournal of Trauma and Acute Care Surgery
Issue number1
StatePublished - 01 2013
Externally publishedYes


  • Distal radius fracture
  • hip fracture
  • osteoporotic fracture


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